ENSG00000159228


Homo sapiens

Features
Gene ID: ENSG00000159228
  
Biological name :CBR1
  
Synonyms : carbonyl reductase 1 / CBR1 / P16152
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 21
Strand: 1
Band: q22.12
Gene start: 36069941
Gene end: 36073166
  
Corresponding Affymetrix probe sets: 209213_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000382143
Ensembl peptide - ENSP00000434613
Ensembl peptide - ENSP00000395132
Ensembl peptide - ENSP00000290349
NCBI entrez gene - 873     See in Manteia.
OMIM - 114830
RefSeq - NM_001757
RefSeq - NM_001286789
RefSeq Peptide - NP_001273718
RefSeq Peptide - NP_001748
swissprot - P16152
swissprot - E9PQ63
swissprot - A8MTM1
Ensembl - ENSG00000159228
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cbr1ENSDARG00000036587Danio rerio
 CBR1ENSGALG00000016027Gallus gallus
 Cbr1ENSMUSG00000051483Mus musculus
 Gm5678ENSMUSG00000082815Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CBR3 / O75828 / carbonyl reductase 3ENSG0000015923171


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR020904  Short-chain dehydrogenase/reductase, conserved site
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0017144 drug metabolic process IDA
 biological_processGO:0019371 cyclooxygenase pathway TAS
 biological_processGO:0030855 epithelial cell differentiation IEP
 biological_processGO:0042373 vitamin K metabolic process IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:1903561 extracellular vesicle HDA
 molecular_functionGO:0004090 carbonyl reductase (NADPH) activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor IDA
 molecular_functionGO:0047021 15-hydroxyprostaglandin dehydrogenase (NADP+) activity IEA
 molecular_functionGO:0050221 prostaglandin-E2 9-reductase activity TAS


Pathways (from Reactome)
Pathway description
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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