ENSG00000160993


Homo sapiens

Features
Gene ID: ENSG00000160993
  
Biological name :ALKBH4
  
Synonyms : ALKBH4 / alkB homolog 4, lysine demethylase / Q9NXW9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: q22.1
Gene start: 102456238
Gene end: 102464876
  
Corresponding Affymetrix probe sets: 222228_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000292566
Ensembl peptide - ENSP00000420362
NCBI entrez gene - 54784     See in Manteia.
OMIM - 613302
RefSeq - XM_005250465
RefSeq - NM_017621
RefSeq - XM_005250464
RefSeq Peptide - NP_060091
swissprot - Q9NXW9
Ensembl - ENSG00000160993
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 alkbh4ENSDARG00000052247Danio rerio
 ALKBH4ENSGALG00000001844Gallus gallus
 Alkbh4ENSMUSG00000039754Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR032857  Alpha-ketoglutarate-dependent dioxygenase alkB homologue 4
 IPR037151  Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006482 protein demethylation IDA
 biological_processGO:0031032 actomyosin structure organization IMP
 biological_processGO:0036090 cleavage furrow ingression IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0070988 demethylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0030496 midbody IEA
 cellular_componentGO:0070938 contractile ring IDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors IDA
 molecular_functionGO:0032451 demethylase activity TAS
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051213 dioxygenase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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