ENSG00000161243


Homo sapiens

Features
Gene ID: ENSG00000161243
  
Biological name :FBXO27
  
Synonyms : F-box protein 27 / FBXO27 / Q8NI29
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.2
Gene start: 38990714
Gene end: 39032785
  
Corresponding Affymetrix probe sets: 235169_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000437662
Ensembl peptide - ENSP00000471267
Ensembl peptide - ENSP00000471772
Ensembl peptide - ENSP00000292853
Ensembl peptide - ENSP00000470015
NCBI entrez gene - 126433     See in Manteia.
OMIM - 609099
RefSeq - XM_017026290
RefSeq - NM_178820
RefSeq Peptide - NP_849142
swissprot - M0R1C3
swissprot - M0QYQ6
swissprot - Q8NI29
swissprot - M0R0I8
Ensembl - ENSG00000161243
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Fbxo27ENSMUSG00000037463Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FBXO17 / Q96EF6 / F-box protein 17ENSG0000026919058
FBXO2 / Q9UK22 / F-box protein 2ENSG0000011666139
FBXO6 / Q9NRD1 / F-box protein 6ENSG0000011666338
NCCRP1 / Q6ZVX7 / non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)ENSG0000018850524
FBXO44 / Q9H4M3 / F-box protein 44ENSG0000013287919


Protein motifs (from Interpro)
Interpro ID Name
 IPR001810  F-box domain
 IPR007397  F-box associated (FBA) domain
 IPR008979  Galactose-binding-like domain superfamily
 IPR036047  F-box-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination TAS
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0019005 SCF ubiquitin ligase complex IDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr