ENSG00000162396


Homo sapiens
ligasePARS2aminoacyl-trnaclassproline-trnaaminoacylationactivitysynthetaseiianticodon-bindingdomaintranslationtrnamitochondrialbindinggpstiiaprokaryotecoresuperfamilyproteinprolyl-trnacytoplasmmitochondrionmatrixnucleotideatp

Features
Gene ID: ENSG00000162396
  
Biological name :PARS2
  
Synonyms : PARS2 / prolyl-tRNA synthetase 2, mitochondrial / Q7L3T8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p32.3
Gene start: 54756898
Gene end: 54764514
  
Corresponding Affymetrix probe sets: 227348_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000360327
NCBI entrez gene - 25973     See in Manteia.
OMIM - 612036
RefSeq - NM_152268
RefSeq Peptide - NP_689481
swissprot - Q7L3T8
Ensembl - ENSG00000162396
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pars2ENSDARG00000044404Danio rerio
 PARS2ENSGALG00000010789Gallus gallus
 Pars2ENSMUSG00000043572Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002314  Aminoacyl-tRNA synthetase, class II (G/ P/ S/T)
 IPR002316  Proline-tRNA ligase, class IIa
 IPR004154  Anticodon-binding
 IPR006195  Aminoacyl-tRNA synthetase, class II
 IPR033730  Prokaryote proline-tRNA ligase core domain
 IPR036621  Anticodon-binding domain superfamily


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabnitrogen compound metabolic processbiosynthetic processbiosynthetic processcellular metabolic proccellular metabolic processprimary metabolic proceprimary metabolic processorganic substance metaborganic substance metabolic processsmall molecule metabolismall molecule metabolic process
organic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingligase activitycatalytic activity, acting on RNAion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingligase activitycatalytic activity, acting on RNAion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingligase activitycatalytic activity, acting on RNAion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingligase activitycatalytic activity, acting on RNAion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingligase activitycatalytic activity, acting on RNAion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingligase activitycatalytic activity, acting on RNAion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingligase activitycatalytic activity, acting on RNAion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingligase activitycatalytic activity, acting on RNAion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingligase activitycatalytic activity, acting on RNAion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingligase activitycatalytic activity, acting on RNAion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic coorganic cyclic compound bindingheterocyclic compheterocyclic compound bindingsmall molecule bismall molecule bindingligase activityligase activitycatalytic activitcatalytic activity, acting on RNAion bindingion bindingcarbohydrate dericarbohydrate derivative bindingdrug bindingdrug binding
cellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumen
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006418 tRNA aminoacylation for protein translation IEA
 biological_processGO:0006433 prolyl-tRNA aminoacylation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005759 mitochondrial matrix IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004812 aminoacyl-tRNA ligase activity IEA
 molecular_functionGO:0004827 proline-tRNA ligase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016874 ligase activity IEA


Pathways (from Reactome)
Pathway description
Mitochondrial tRNA aminoacylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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