ENSG00000162694


Homo sapiens

Features
Gene ID: ENSG00000162694
  
Biological name :EXTL2
  
Synonyms : exostosin like glycosyltransferase 2 / EXTL2 / Q9UBQ6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p21.2
Gene start: 100872372
Gene end: 100895998
  
Corresponding Affymetrix probe sets: 209537_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000444385
Ensembl peptide - ENSP00000359132
Ensembl peptide - ENSP00000392255
Ensembl peptide - ENSP00000403363
Ensembl peptide - ENSP00000359131
NCBI entrez gene - 2135     See in Manteia.
OMIM - 602411
RefSeq - XM_017000651
RefSeq - NM_001033025
RefSeq - NM_001261440
RefSeq - NM_001261441
RefSeq - NM_001261442
RefSeq - NM_001439
RefSeq - XM_005270621
RefSeq - XM_011540994
RefSeq - XM_011540995
RefSeq - XM_011540996
RefSeq Peptide - NP_001248369
RefSeq Peptide - NP_001248370
RefSeq Peptide - NP_001248371
RefSeq Peptide - NP_001430
RefSeq Peptide - NP_001028197
swissprot - F5GZK1
swissprot - Q9UBQ6
swissprot - C9IYF5
swissprot - C9JEG3
Ensembl - ENSG00000162694
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 extl2ENSDARG00000063191Danio rerio
 EXTL2ENSGALG00000027984Gallus gallus
 Extl2ENSMUSG00000027963Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EXTL3 / O43909 / exostosin like glycosyltransferase 3ENSG0000001223229
EXT1 / Q16394 / exostosin glycosyltransferase 1ENSG0000018219728
EXT2 / Q93063 / exostosin glycosyltransferase 2ENSG0000015134826
EXTL1 / Q92935 / exostosin like glycosyltransferase 1ENSG0000015800824


Protein motifs (from Interpro)
Interpro ID Name
 IPR015338  Exostosin , C-terminal
 IPR029044  Nucleotide-diphospho-sugar transferases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006044 N-acetylglucosamine metabolic process IEA
 biological_processGO:0015012 heparan sulfate proteoglycan biosynthetic process IEA
 biological_processGO:0019276 UDP-N-acetylgalactosamine metabolic process IEA
 biological_processGO:0036498 IRE1-mediated unfolded protein response TAS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity IEA
 molecular_functionGO:0005539 glycosaminoglycan binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0030145 manganese ion binding IEA
 molecular_functionGO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity IEA


Pathways (from Reactome)
Pathway description
XBP1(S) activates chaperone genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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