ENSG00000165501


Homo sapiens
repeatLRR1leucine-richproteinubiquitinationtypicalsubtypeleucinerichdomainsuperfamilysignaltransductionpost-translationalmodificationcytoplasmcytosolplasmamembranebindingisomeraseactivityneddylationantigenprocessingproteasomedegradation

Features
Gene ID: ENSG00000165501
  
Biological name :LRR1
  
Synonyms : leucine rich repeat protein 1 / LRR1 / Q96L50
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q21.3
Gene start: 49598697
Gene end: 49614672
  
Corresponding Affymetrix probe sets: 235113_at (Human Genome U133 Plus 2.0 Array)   242154_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000298288
Ensembl peptide - ENSP00000315628
Ensembl peptide - ENSP00000439452
Ensembl peptide - ENSP00000452355
NCBI entrez gene - 122769     See in Manteia.
OMIM - 609193
RefSeq - NM_152329
RefSeq - NM_203467
RefSeq Peptide - NP_689542
RefSeq Peptide - NP_982292
swissprot - Q96L50
swissprot - G3V5H2
swissprot - Q6P393
Ensembl - ENSG00000165501
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:77287ENSDARG00000104448Danio rerio
 LRR1ENSGALG00000012230Gallus gallus
 Lrr1ENSMUSG00000034883Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LRRC58 / Q96CX6 / leucine rich repeat containing 58ENSG0000016342823


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR025875  Leucine rich repeat 4
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
cell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcell communicationcellular response to stcellular response to stimulusnitrogen compound metabnitrogen compound metabolic processcellular metabolic proccellular metabolic processprimary metabolic proceprimary metabolic processorganic substance metaborganic substance metabolic process
protein bindingisomerase activityprotein bindingisomerase activityprotein bindingisomerase activityprotein bindingisomerase activityprotein bindingisomerase activityprotein bindingisomerase activityprotein bindingisomerase activityprotein bindingisomerase activityprotein bindingisomerase activityprotein bindingisomerase activityprotein bindingprotein bindingisomerase activityisomerase activity
cellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellcellmembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016853 isomerase activity IEA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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