ENSG00000165804


Homo sapiens
regulationbindingZNF219rnapolymeraseiihreceptorzincfingerdna-templateddnaactivityhistaminecproximalpromotersequence-specificringfyvephd-type-typesuperfamilyneurotransmitterlevelssignaltransductiong-proteincoupledsignaling

Features
Gene ID: ENSG00000165804
  
Biological name :ZNF219
  
Synonyms : Q9P2Y4 / zinc finger protein 219 / ZNF219
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q11.2
Gene start: 21090046
Gene end: 21104722
  
Corresponding Affymetrix probe sets: 1558594_at (Human Genome U133 Plus 2.0 Array)   219314_s_at (Human Genome U133 Plus 2.0 Array)   222864_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000451969
Ensembl peptide - ENSP00000451595
Ensembl peptide - ENSP00000451890
Ensembl peptide - ENSP00000354206
Ensembl peptide - ENSP00000388558
Ensembl peptide - ENSP00000392401
Ensembl peptide - ENSP00000450609
Ensembl peptide - ENSP00000450803
Ensembl peptide - ENSP00000450900
Ensembl peptide - ENSP00000451212
NCBI entrez gene - 51222     See in Manteia.
OMIM - 605036
RefSeq - XM_017021355
RefSeq - NM_001101672
RefSeq - NM_001102454
RefSeq - NM_016423
RefSeq - XM_005267739
RefSeq - XM_006720163
RefSeq - XM_006720164
RefSeq - XM_011536825
RefSeq - XM_017021354
RefSeq Peptide - NP_001095924
RefSeq Peptide - NP_057507
RefSeq Peptide - NP_001095142
swissprot - G3V3F2
swissprot - G3V452
swissprot - G3V4M7
swissprot - G3V4T1
swissprot - G3V2E3
swissprot - Q9P2Y4
swissprot - G3V2Q8
swissprot - G3V2W3
Ensembl - ENSG00000165804
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 F1QQA8ENSDARG00000079738Danio rerio
 Q6IQX8ENSMUSG00000049295Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O15090 / ZNF536 / zinc finger protein 536ENSG0000019859740
Q92618 / ZNF516 / zinc finger protein 516ENSG0000010149321
O75362 / ZNF217 / zinc finger protein 217ENSG0000017194020


Protein motifs (from Interpro)
Interpro ID Name
 IPR003980  Histamine H3 receptor
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of biological qualitycell communicationcellular response to stimulusanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of biological qualitycell communicationcellular response to stimulusanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of biological qualitycell communicationcellular response to stimulusanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of biological qualitycell communicationcellular response to stimulusanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of biological qualitycell communicationcellular response to stimulusanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of biological qualitycell communicationcellular response to stimulusanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of biological qualitycell communicationcellular response to stimulusanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of biological qualitycell communicationcellular response to stimulusanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of biological qualitycell communicationcellular response to stimulusanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of biological qualitycell communicationcellular response to stimulusanatomical structure developmentcellular developmental processnitrogen componitrogen compound metabolic processbiosynthetic pbiosynthetic processcellular metabcellular metabolic processprimary metaboprimary metabolic processorganic substaorganic substance metabolic processregulation of regulation of biological qualitycell communicacell communicationcellular respocellular response to stimulusanatomical stranatomical structure developmentcellular develcellular developmental process
organic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activityprotein bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activityprotein bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activityprotein bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activityprotein bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activityprotein bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activityprotein bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activityprotein bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activityprotein bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activityprotein bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activityprotein bindingion bindingorganic cyclic compoundorganic cyclic compound bindingheterocyclic compound bheterocyclic compound bindingDNA-binding transcriptiDNA-binding transcription factor activitysignaling receptor actisignaling receptor activityprotein bindingprotein bindingion bindingion binding
cellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellcellorganelleorganellemembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0001505 regulation of neurotransmitter levels IEA
 biological_processGO:0006351 transcription, DNA-templated TAS
 biological_processGO:0006355 regulation of transcription, DNA-templated IMP
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0032332 positive regulation of chondrocyte differentiation IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0060174 limb bud formation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0004969 histamine receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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