ENSG00000167925


Homo sapiens
neutrophilgranulelumenGHDCghfamilybiologicalprocessextracellularregionnucleusnuclearenvelopeendoplasmicreticulummembranesecretoryspecificmolecularfunction

Features
Gene ID: ENSG00000167925
  
Biological name :GHDC
  
Synonyms : GH3 domain containing / GHDC / Q8N2G8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q21.2
Gene start: 42188799
Gene end: 42194532
  
Corresponding Affymetrix probe sets: 227159_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000467585
Ensembl peptide - ENSP00000467660
Ensembl peptide - ENSP00000468790
Ensembl peptide - ENSP00000301671
Ensembl peptide - ENSP00000399952
Ensembl peptide - ENSP00000410945
Ensembl peptide - ENSP00000465315
Ensembl peptide - ENSP00000465924
NCBI entrez gene - 84514     See in Manteia.
OMIM - 608587
RefSeq - NM_032484
RefSeq - NM_001142623
RefSeq Peptide - NP_001136095
RefSeq Peptide - NP_115873
swissprot - K7ESN3
swissprot - A0A024R1Y7
swissprot - Q8N2G8
swissprot - K7EJT7
swissprot - K7EL54
swissprot - K7EQ41
Ensembl - ENSG00000167925
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ghdcENSDARG00000055569Danio rerio
 GHDCENSGALG00000003333Gallus gallus
 GhdcENSMUSG00000017747Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004993  GH3 family


Gene Ontology (GO)
immune responseestablishment of localizationcell activationimmune effector processimmune responseestablishment of localizationcell activationimmune effector processimmune responseestablishment of localizationcell activationimmune effector processimmune responseestablishment of localizationcell activationimmune effector processimmune responseestablishment of localizationcell activationimmune effector processimmune responseestablishment of localizationcell activationimmune effector processimmune responseestablishment of localizationcell activationimmune effector processimmune responseestablishment of localizationcell activationimmune effector processimmune responseestablishment of localizationcell activationimmune effector processimmune responseestablishment of localizationcell activationimmune effector processimmune responseimmune responseestablishment of localizationestablishment of localizationcell activationcell activationimmune effector processimmune effector process
extracellular regioncellorganellemembranemembrane-enclosed lumenextracellular regioncellorganellemembranemembrane-enclosed lumenextracellular regioncellorganellemembranemembrane-enclosed lumenextracellular regioncellorganellemembranemembrane-enclosed lumenextracellular regioncellorganellemembranemembrane-enclosed lumenextracellular regioncellorganellemembranemembrane-enclosed lumenextracellular regioncellorganellemembranemembrane-enclosed lumenextracellular regioncellorganellemembranemembrane-enclosed lumenextracellular regioncellorganellemembranemembrane-enclosed lumenextracellular regioncellorganellemembranemembrane-enclosed lumenextracellular regionextracellular regioncellcellorganelleorganellemembranemembranemembrane-enclosed lumenmembrane-enclosed lumen
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0043312 neutrophil degranulation TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005635 nuclear envelope IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0034774 secretory granule lumen TAS
 cellular_componentGO:0035580 specific granule lumen TAS
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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