ENSG00000169474


Homo sapiens

Features
Gene ID: ENSG00000169474
  
Biological name :SPRR1A
  
Synonyms : P35321 / small proline rich protein 1A / SPRR1A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q21.3
Gene start: 152985231
Gene end: 152985500
  
Corresponding Affymetrix probe sets: 213796_at (Human Genome U133 Plus 2.0 Array)   214549_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000357751
NCBI entrez gene - 6698     See in Manteia.
OMIM - 182265
RefSeq - NM_005987
RefSeq - NM_001199828
RefSeq Peptide - NP_001186757
RefSeq Peptide - NP_005978
swissprot - P35321
Ensembl - ENSG00000169474
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P22528 / SPRR1B / small proline rich protein 1BENSG0000016946996
SPRR3 / Q9UBC9 / small proline rich protein 3ENSG0000016320969


Protein motifs (from Interpro)
Interpro ID Name
 IPR003302  Cornifin (SPRR1)
 IPR026075  Small proline-rich protein/late cornified envelope protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008544 epidermis development TAS
 biological_processGO:0018149 peptide cross-linking IDA
 biological_processGO:0030216 keratinocyte differentiation IDA
 biological_processGO:0031424 keratinization IEA
 biological_processGO:0070268 cornification TAS
 cellular_componentGO:0001533 cornified envelope IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005198 structural molecule activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030280 structural constituent of epidermis IDA
 molecular_functionGO:0030674 protein binding, bridging IDA


Pathways (from Reactome)
Pathway description
Formation of the cornified envelope


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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