ENSG00000170419


Homo sapiens
regulationVSTM2Adomaincellimmunoglobulindifferentiationfatmembranesubtypev-setfoldsuperfamilygeneexpressionlipidstoragewhiteproliferationcellularresponsebmpstimulusbrownextracellularregionplasmaintegralcomponentidenticalprotein

Features
Gene ID: ENSG00000170419
  
Biological name :VSTM2A
  
Synonyms : Q8TAG5 / V-set and transmembrane domain containing 2A / VSTM2A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: p11.2
Gene start: 54542325
Gene end: 54571080
  
Corresponding Affymetrix probe sets: 1554530_at (Human Genome U133 Plus 2.0 Array)   230117_at (Human Genome U133 Plus 2.0 Array)   236308_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000384967
Ensembl peptide - ENSP00000303108
Ensembl peptide - ENSP00000384103
Ensembl peptide - ENSP00000384701
NCBI entrez gene - 222008     See in Manteia.
RefSeq - XM_017011841
RefSeq - NM_001301009
RefSeq - NM_001317843
RefSeq - NM_182546
RefSeq - XM_006715665
RefSeq - XM_006715666
RefSeq Peptide - NP_001304772
RefSeq Peptide - NP_872352
RefSeq Peptide - NP_001287938
swissprot - F8W8J5
swissprot - Q8TAG5
swissprot - B5MCX6
Ensembl - ENSG00000170419
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 VSTM2AENSDARG00000021909Danio rerio
 VSTM2AENSGALG00000041764Gallus gallus
 Q8R0A6ENSMUSG00000048834Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A6NLU5 / VSTM2B / V-set and transmembrane domain containing 2BENSG0000018713533
Q96N03 / VSTM2L / V-set and transmembrane domain containing 2 likeENSG0000013282127


Protein motifs (from Interpro)
Interpro ID Name
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
organic substance metabolic processmacromolecule localizationregulation of biological qualitycellular developmental processfat cell proliferationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusorganic substance metabolic processmacromolecule localizationregulation of biological qualitycellular developmental processfat cell proliferationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusorganic substance metabolic processmacromolecule localizationregulation of biological qualitycellular developmental processfat cell proliferationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusorganic substance metabolic processmacromolecule localizationregulation of biological qualitycellular developmental processfat cell proliferationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusorganic substance metabolic processmacromolecule localizationregulation of biological qualitycellular developmental processfat cell proliferationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusorganic substance metabolic processmacromolecule localizationregulation of biological qualitycellular developmental processfat cell proliferationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusorganic substance metabolic processmacromolecule localizationregulation of biological qualitycellular developmental processfat cell proliferationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusorganic substance metabolic processmacromolecule localizationregulation of biological qualitycellular developmental processfat cell proliferationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusorganic substance metabolic processmacromolecule localizationregulation of biological qualitycellular developmental processfat cell proliferationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusorganic substance metabolic processmacromolecule localizationregulation of biological qualitycellular developmental processfat cell proliferationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusorganic substanceorganic substance metabolic processmacromolecule locmacromolecule localizationregulation of bioregulation of biological qualitycellular developmcellular developmental processfat cell proliferfat cell proliferationresponse to endogresponse to endogenous stimulusresponse to chemiresponse to chemicalcellular responsecellular response to stimulus
protein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein binding
extracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regionextracellular regioncellcellmembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0010884 positive regulation of lipid storage IMP
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0070352 positive regulation of white fat cell proliferation IMP
 biological_processGO:0071773 cellular response to BMP stimulus ISS
 biological_processGO:0090336 positive regulation of brown fat cell differentiation IMP
 cellular_componentGO:0005576 extracellular region ISS
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016021 integral component of membrane IBA
 molecular_functionGO:0042802 identical protein binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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