ENSG00000171219


Homo sapiens

Features
Gene ID: ENSG00000171219
  
Biological name :CDC42BPG
  
Synonyms : CDC42 binding protein kinase gamma / CDC42BPG / Q6DT37
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q13.1
Gene start: 64823387
Gene end: 64844569
  
Corresponding Affymetrix probe sets: 1564823_at (Human Genome U133 Plus 2.0 Array)   1569044_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000345133
NCBI entrez gene - 55561     See in Manteia.
OMIM - 613991
RefSeq - XM_017017999
RefSeq - NM_017525
RefSeq - XM_017017997
RefSeq - XM_017017998
RefSeq - XM_011545155
RefSeq - XM_011545156
RefSeq - XM_011545157
RefSeq - XM_011545158
RefSeq - XM_011545159
RefSeq - XM_011545160
RefSeq - XM_011545161
RefSeq - XM_017017996
RefSeq Peptide - NP_059995
swissprot - Q6DT37
Ensembl - ENSG00000171219
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q80UW5ENSMUSG00000024769Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q5VT25 / CDC42BPA / CDC42 binding protein kinase alphaENSG0000014377647
Q9Y5S2 / CDC42BPB / CDC42 binding protein kinase betaENSG0000019875247
CIT / O14578 / citron rho-interacting serine/threonine kinaseENSG0000012296626
ROCK1 / Q13464 / Rho associated coiled-coil containing protein kinase 1ENSG0000006790022
ROCK2 / O75116 / Rho associated coiled-coil containing protein kinase 2ENSG0000013431821
DMPK / Q09013 / DM1 protein kinaseENSG0000010493619
STK38 / Q15208 / serine/threonine kinase 38ENSG0000011207911
LATS2 / Q9NRM7 / large tumor suppressor kinase 2ENSG0000015045711
Q9Y2H1 / STK38L / serine/threonine kinase 38 likeENSG0000021145511
LATS1 / O95835 / large tumor suppressor kinase 1ENSG0000013102310


Protein motifs (from Interpro)
Interpro ID Name
 IPR000095  CRIB domain
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR001180  Citron homology (CNH) domain
 IPR001849  Pleckstrin homology domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR011993  PH-like domain superfamily
 IPR014930  Myotonic dystrophy protein kinase, coiled coil
 IPR017441  Protein kinase, ATP binding site
 IPR033235  Serine/threonine-protein kinase MRCK gamma


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation NAS
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0031532 actin cytoskeleton reorganization ISS
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0031252 cell leading edge IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IDA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding NAS
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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