ENSG00000171864


Homo sapiens
proteinmembranePRNDdoppelionprionbeta-ribbondomaincopperplasmaanchoredcomponentbindingprion-likesuperfamilyc-terminallipidationcellularhomeostasissinglefertilizationacrosomereactionhomooligomerizationextracellularregionexternalsidemetalpost-translationalmodification

Features
Gene ID: ENSG00000171864
  
Biological name :PRND
  
Synonyms : prion like protein doppel / PRND / Q9UKY0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: p13
Gene start: 4721910
Gene end: 4728460
  
Corresponding Affymetrix probe sets: 222106_at (Human Genome U133 Plus 2.0 Array)   223813_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000306900
NCBI entrez gene - 23627     See in Manteia.
OMIM - 604263
RefSeq - NM_012409
RefSeq Peptide - NP_036541
swissprot - Q9UKY0
Ensembl - ENSG00000171864
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PrnENSMUSG00000098754Mus musculus
 PrndENSMUSG00000027338Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR021566  Prion-like protein Doppel
 IPR022416  Prion/Doppel protein, beta-ribbon domain
 IPR036924  Prion/Doppel beta-ribbon domain superfamily


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of biological qualitycellular component organizationcellular component biogenesisnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of biological qualitycellular component organizationcellular component biogenesisnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of biological qualitycellular component organizationcellular component biogenesisnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of biological qualitycellular component organizationcellular component biogenesisnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of biological qualitycellular component organizationcellular component biogenesisnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of biological qualitycellular component organizationcellular component biogenesisnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of biological qualitycellular component organizationcellular component biogenesisnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of biological qualitycellular component organizationcellular component biogenesisnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of biological qualitycellular component organizationcellular component biogenesisnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of biological qualitycellular component organizationcellular component biogenesisnitrogen compoundnitrogen compound metabolic processbiosynthetic procbiosynthetic processcellular metabolicellular metabolic processprimary metabolicprimary metabolic processorganic substanceorganic substance metabolic processregulation of bioregulation of biological qualitycellular componencellular component organizationcellular componencellular component biogenesis
ion bindingion bindingion bindingion bindingion bindingion bindingion bindingion bindingion bindingion bindingion bindingion binding
extracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regionextracellular regioncellcellmembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0006501 C-terminal protein lipidation TAS
 biological_processGO:0006878 cellular copper ion homeostasis IBA
 biological_processGO:0007338 single fertilization IEA
 biological_processGO:0007340 acrosome reaction ISS
 biological_processGO:0051260 protein homooligomerization IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0031362 anchored component of external side of plasma membrane ISS
 molecular_functionGO:0005507 copper ion binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Post-translational modification: synthesis of GPI-anchored proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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