ENSG00000172005


Homo sapiens

Features
Gene ID: ENSG00000172005
  
Biological name :MAL
  
Synonyms : MAL / mal, T cell differentiation protein / P21145
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q11.1
Gene start: 95025677
Gene end: 95053996
  
Corresponding Affymetrix probe sets: 204777_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000322860
Ensembl peptide - ENSP00000304924
Ensembl peptide - ENSP00000306568
Ensembl peptide - ENSP00000310880
NCBI entrez gene - 4118     See in Manteia.
OMIM - 188860
RefSeq - NM_022438
RefSeq - NM_002371
RefSeq - NM_022439
RefSeq - NM_022440
RefSeq Peptide - NP_002362
RefSeq Peptide - NP_071883
RefSeq Peptide - NP_071884
RefSeq Peptide - NP_071885
swissprot - P21145
swissprot - A0A024RE19
Ensembl - ENSG00000172005
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 malENSDARG00000030094Danio rerio
 zgc:153665ENSDARG00000043442Danio rerio
 zgc:158773ENSDARG00000070401Danio rerio
 MALENSGALG00000008552Gallus gallus
 MalENSMUSG00000027375Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MALL / Q13021 / mal, T cell differentiation protein likeENSG0000014406339
MAL2 / Q969L2 / mal, T cell differentiation protein 2 (gene/pseudogene)ENSG0000014767639


Protein motifs (from Interpro)
Interpro ID Name
 IPR008253  Marvel domain
 IPR013295  Myelin and lymphocyte (MAL) protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001766 membrane raft polarization TAS
 biological_processGO:0006915 apoptotic process NAS
 biological_processGO:0007417 central nervous system development TAS
 biological_processGO:0030154 cell differentiation TAS
 biological_processGO:0042552 myelination TAS
 biological_processGO:0045176 apical protein localization TAS
 biological_processGO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors IEA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 cellular_componentGO:0016324 apical plasma membrane TAS
 cellular_componentGO:0045121 membrane raft IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding TAS
 molecular_functionGO:0016505 peptidase activator activity involved in apoptotic process NAS
 molecular_functionGO:0019911 structural constituent of myelin sheath IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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