ENSG00000173431


Homo sapiens

Features
Gene ID: ENSG00000173431
  
Biological name :RNASE8
  
Synonyms : Q8TDE3 / ribonuclease A family member 8 / RNASE8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q11.2
Gene start: 21057822
Gene end: 21058455
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000311398
NCBI entrez gene - 122665     See in Manteia.
OMIM - 612485
RefSeq - NM_138331
RefSeq Peptide - NP_612204
swissprot - Q8TDE3
Ensembl - ENSG00000173431
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9H1E1 / RNASE7 / ribonuclease A family member 7ENSG0000016579977
Q93091 / RNASE6 / ribonuclease A family member k6ENSG0000016941352
P10153 / RNASE2 / ribonuclease A family member 2ENSG0000016938543
P12724 / RNASE3 / ribonuclease A family member 3ENSG0000016939738


Protein motifs (from Interpro)
Interpro ID Name
 IPR001427  Pancreatic ribonuclease
 IPR023411  Ribonuclease A, active site
 IPR023412  Ribonuclease A-domain
 IPR036816  Ribonuclease A-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0045087 innate immune response IMP
 biological_processGO:0050829 defense response to Gram-negative bacterium IMP
 biological_processGO:0050830 defense response to Gram-positive bacterium IDA
 biological_processGO:0061760 antifungal innate immune response IDA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 biological_processGO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004519 endonuclease activity IEA
 molecular_functionGO:0004522 ribonuclease A activity IDA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Antimicrobial peptides


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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