ENSG00000174136


Homo sapiens

Features
Gene ID: ENSG00000174136
  
Biological name :RGMB
  
Synonyms : Q6NW40 / repulsive guidance molecule BMP co-receptor b / RGMB
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q15
Gene start: 98768650
Gene end: 98798643
  
Corresponding Affymetrix probe sets: 226989_at (Human Genome U133 Plus 2.0 Array)   227339_at (Human Genome U133 Plus 2.0 Array)   227340_s_at (Human Genome U133 Plus 2.0 Array)   242450_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000308219
Ensembl peptide - ENSP00000423256
NCBI entrez gene - 285704     See in Manteia.
OMIM - 612687
RefSeq - XM_017009391
RefSeq - NM_001012761
RefSeq - XM_011543345
RefSeq - XM_011543347
RefSeq - XM_017009390
RefSeq - XM_005271966
RefSeq Peptide - NP_001012779
swissprot - Q6NW40
swissprot - J3KNF6
Ensembl - ENSG00000174136
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rgmbENSDARG00000079323Danio rerio
 RGMBENSGALG00000015284Gallus gallus
 RgmbENSMUSG00000048027Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RGMA / Q96B86 / repulsive guidance molecule BMP co-receptor aENSG0000018217545
HFE2 / Q6ZVN8 / hemochromatosis type 2 (juvenile)ENSG0000016850938


Protein motifs (from Interpro)
Interpro ID Name
 IPR009496  Repulsive guidance molecule, C-terminal
 IPR010536  Repulsive guidance molecule, N-terminal
 IPR016123  Mog1/PsbP, alpha/beta/alpha sandwich
 IPR033608  RGM domain family member B


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion ISS
 biological_processGO:0007165 signal transduction ISS
 biological_processGO:0030509 BMP signaling pathway ISS
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISS
 cellular_componentGO:0005793 endoplasmic reticulum-Golgi intermediate compartment ISS
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0046658 anchored component of plasma membrane ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015026 coreceptor activity IBA
 molecular_functionGO:0042802 identical protein binding ISS


Pathways (from Reactome)
Pathway description
Netrin-1 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000067141 NEO1 / Q92859 / neogenin 1  / complex / reaction






 

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