ENSG00000174307


Homo sapiens

Features
Gene ID: ENSG00000174307
  
Biological name :PHLDA3
  
Synonyms : PHLDA3 / pleckstrin homology like domain family A member 3 / Q9Y5J5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q32.1
Gene start: 201464383
Gene end: 201469237
  
Corresponding Affymetrix probe sets: 218634_at (Human Genome U133 Plus 2.0 Array)   235534_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000356280
Ensembl peptide - ENSP00000356278
NCBI entrez gene - 23612     See in Manteia.
OMIM - 607054
RefSeq - NM_012396
RefSeq Peptide - NP_036528
swissprot - Q9Y5J5
Ensembl - ENSG00000174307
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PHLDA3ENSGALG00000019802Gallus gallus
 Phlda3ENSMUSG00000041801Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PHLDA1 / Q8WV24 / pleckstrin homology like domain family A member 1ENSG0000013928952
PHLDA2 / Q53GA4 / pleckstrin homology like domain family A member 2ENSG0000018164947


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0009653 anatomical structure morphogenesis TAS
 biological_processGO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IDA
 biological_processGO:0043065 positive regulation of apoptotic process IDA
 biological_processGO:0051898 negative regulation of protein kinase B signaling IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IDA
 molecular_functionGO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding IDA
 molecular_functionGO:0010314 phosphatidylinositol-5-phosphate binding IDA
 molecular_functionGO:0032266 phosphatidylinositol-3-phosphate binding IDA
 molecular_functionGO:0043325 phosphatidylinositol-3,4-bisphosphate binding IDA
 molecular_functionGO:0080025 phosphatidylinositol-3,5-bisphosphate binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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