ENSG00000178342


Homo sapiens

Features
Gene ID: ENSG00000178342
  
Biological name :KCNG2
  
Synonyms : KCNG2 / potassium voltage-gated channel modifier subfamily G member 2 / Q9UJ96
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: 1
Band: q23
Gene start: 79863668
Gene end: 79900184
  
Corresponding Affymetrix probe sets: 208550_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000315654
NCBI entrez gene - 26251     See in Manteia.
OMIM - 605696
RefSeq - XM_017025705
RefSeq - NM_012283
RefSeq - XM_011525920
RefSeq - XM_017025704
RefSeq - XM_011525918
RefSeq Peptide - NP_036415
swissprot - Q9UJ96
Ensembl - ENSG00000178342
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kcng2ENSDARG00000035961Danio rerio
 KCNG2ENSGALG00000031754Gallus gallus
 Kcng2ENSMUSG00000059852Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KCNG1 / Q9UIX4 / potassium voltage-gated channel modifier subfamily G member 1ENSG0000002655956
KCNG4 / Q8TDN1 / potassium voltage-gated channel modifier subfamily G member 4ENSG0000016841856
KCNG3 / Q8TAE7 / potassium voltage-gated channel modifier subfamily G member 3ENSG0000017112638
KCNB1 / Q14721 / potassium voltage-gated channel subfamily B member 1ENSG0000015844536
KCNB2 / Q92953 / potassium voltage-gated channel subfamily B member 2ENSG0000018267436
KCNS1 / Q96KK3 / potassium voltage-gated channel modifier subfamily S member 1ENSG0000012413434
KCNV1 / Q6PIU1 / potassium voltage-gated channel modifier subfamily V member 1ENSG0000016479433
KCNS3 / Q9BQ31 / potassium voltage-gated channel modifier subfamily S member 3ENSG0000017074531
KCNS2 / Q9ULS6 / potassium voltage-gated channel modifier subfamily S member 2ENSG0000015648629
KCNF1 / Q9H3M0 / potassium voltage-gated channel modifier subfamily F member 1ENSG0000016297528
KCNV2 / Q8TDN2 / potassium voltage-gated channel modifier subfamily V member 2ENSG0000016826328


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR003131  Potassium channel tetramerisation-type BTB domain
 IPR003968  Potassium channel, voltage dependent, Kv
 IPR003969  Potassium channel, voltage dependent, Kv6
 IPR005821  Ion transport domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR028325  Voltage-gated potassium channel


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport TAS
 biological_processGO:0008016 regulation of heart contraction TAS
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0050796 regulation of insulin secretion TAS
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0008076 voltage-gated potassium channel complex TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IEA
 molecular_functionGO:0005251 delayed rectifier potassium channel activity TAS
 molecular_functionGO:0005267 potassium channel activity IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Voltage gated Potassium channels
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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