ENSG00000180089


Homo sapiens
hydrolaseactivityTMEM86Bmembraneetheryhhn-likephosphatidylcholineacyl-chainremodelinglipidmetabolicprocesscytoplasmendoplasmicreticulumintegralcomponentproteinbindingalkenylglycerophosphocholinealkenylglycerophosphoethanolamineacylchainremodellingpc

Features
Gene ID: ENSG00000180089
  
Biological name :TMEM86B
  
Synonyms : Q8N661 / TMEM86B / transmembrane protein 86B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.42
Gene start: 55226639
Gene end: 55229264
  
Corresponding Affymetrix probe sets: 229736_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000321038
NCBI entrez gene - 255043     See in Manteia.
OMIM - 617806
RefSeq - NM_173804
RefSeq - XM_017026554
RefSeq Peptide - NP_776165
swissprot - Q8N661
Ensembl - ENSG00000180089
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tmem86bENSDARG00000038296Danio rerio
 Q497J1ENSMUSG00000045282Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8N2M4 / TMEM86A / transmembrane protein 86AENSG0000015111735


Protein motifs (from Interpro)
Interpro ID Name
 IPR012506  YhhN-like


Gene Ontology (GO)
nitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic nitrogen compound metabolic processcellular metabolic processcellular metabolic processprimary metabolic processprimary metabolic processorganic substance metabolic organic substance metabolic processsmall molecule metabolic prosmall molecule metabolic process
protein bindinghydrolase activityprotein bindinghydrolase activityprotein bindinghydrolase activityprotein bindinghydrolase activityprotein bindinghydrolase activityprotein bindinghydrolase activityprotein bindinghydrolase activityprotein bindinghydrolase activityprotein bindinghydrolase activityprotein bindinghydrolase activityprotein bindingprotein bindinghydrolase activityhydrolase activity
cellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellcellmembranemembraneorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0036151 phosphatidylcholine acyl-chain remodeling TAS
 biological_processGO:0046485 ether lipid metabolic process IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016803 ether hydrolase activity TAS
 molecular_functionGO:0047408 alkenylglycerophosphocholine hydrolase activity IEA
 molecular_functionGO:0047409 alkenylglycerophosphoethanolamine hydrolase activity IDA


Pathways (from Reactome)
Pathway description
Acyl chain remodelling of PC


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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