ENSG00000183018


Homo sapiens

Features
Gene ID: ENSG00000183018
  
Biological name :SPNS2
  
Synonyms : Q8IVW8 / sphingolipid transporter 2 / SPNS2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: p13.2
Gene start: 4498838
Gene end: 4539035
  
Corresponding Affymetrix probe sets: 225671_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000333292
Ensembl peptide - ENSP00000461410
NCBI entrez gene - 124976     See in Manteia.
OMIM - 612584
RefSeq - NM_001124758
RefSeq Peptide - NP_001118230
swissprot - Q8IVW8
swissprot - I3L4N9
Ensembl - ENSG00000183018
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SPNS2ENSGALG00000001387Gallus gallus
 2 ENSMUSG00000040447Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SPNS1 / Q9H2V7 / sphingolipid transporter 1 (putative)ENSG0000016968248
SPNS3 / Q6ZMD2 / sphingolipid transporter 3 (putative)ENSG0000018255740


Protein motifs (from Interpro)
Interpro ID Name
 IPR011701  Major facilitator superfamily
 IPR020846  Major facilitator superfamily domain
 IPR036259  MFS transporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001782 B cell homeostasis IEA
 biological_processGO:0002260 lymphocyte homeostasis IEA
 biological_processGO:0002920 regulation of humoral immune response IEA
 biological_processGO:0003376 sphingosine-1-phosphate signaling pathway IEA
 biological_processGO:0006665 sphingolipid metabolic process IEA
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0040011 locomotion IBA
 biological_processGO:0043029 T cell homeostasis IEA
 biological_processGO:0048073 regulation of eye pigmentation IEA
 biological_processGO:0048535 lymph node development IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0060348 bone development IEA
 biological_processGO:0072676 lymphocyte migration IEA
 cellular_componentGO:0005765 lysosomal membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031982 vesicle IBA
 molecular_functionGO:0046624 sphingolipid transporter activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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