ENSG00000183695


Homo sapiens

Features
Gene ID: ENSG00000183695
  
Biological name :MRGPRX2
  
Synonyms : MAS related GPR family member X2 / MRGPRX2 / Q96LB1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: p15.1
Gene start: 19054455
Gene end: 19060681
  
Corresponding Affymetrix probe sets: 1553889_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000333800
NCBI entrez gene - 117194     See in Manteia.
OMIM - 607228
RefSeq - NM_054030
RefSeq - NM_001303615
RefSeq Peptide - NP_001290544
RefSeq Peptide - NP_473371
swissprot - Q96LB1
Ensembl - ENSG00000183695
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Mrgpra1ENSMUSG00000050650Mus musculus
 Mrgpra2aENSMUSG00000093973Mus musculus
 Mrgpra2bENSMUSG00000096719Mus musculus
 Mrgpra3ENSMUSG00000078698Mus musculus
 Mrgpra9ENSMUSG00000074111Mus musculus
 Q91WW2ENSMUSG00000067173Mus musculus
 Q91ZC6ENSMUSG00000052303Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96LB2 / MRGPRX1 / MAS related GPR family member X1ENSG0000017025563
Q96LA9 / MRGPRX4 / MAS related GPR family member X4ENSG0000017981762
Q96LB0 / MRGPRX3 / MAS related GPR family member X3ENSG0000017982662
MRGPRD / Q8TDS7 / MAS related GPR family member DENSG0000017293835
MRGPRE / Q86SM8 / MAS related GPR family member EENSG0000018435034
MRGPRF / Q96AM1 / MAS related GPR family member FENSG0000017293533
MAS1 / P04201 / MAS1 proto-oncogene, G protein-coupled receptorENSG0000013036832
MAS1L / P35410 / MAS1 proto-oncogene like, G protein-coupled receptorENSG0000020468730
MRGPRG / Q86SM5 / MAS related GPR family member GENSG0000018217029


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR017452  GPCR, rhodopsin-like, 7TM
 IPR026234  Mas-related G protein-coupled receptor family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0019233 sensory perception of pain NAS
 biological_processGO:0030431 sleep NAS
 biological_processGO:0032467 positive regulation of cytokinesis IMP
 biological_processGO:0043303 mast cell degranulation IDA
 biological_processGO:0045576 mast cell activation IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IC
 cellular_componentGO:0042629 mast cell granule IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IDA
 molecular_functionGO:0042923 neuropeptide binding IPI
 molecular_functionGO:1990595 mast cell secretagogue receptor activity ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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