ENSG00000184163


Homo sapiens
regulationC1QTNF12glucosesignalingdomainreceptoractivityinsulinresponseimportproteinextracellularcqtumournecrosisfactor-likesuperfamilymetabolicprocesssecretioninvolvedcellularstimulusgluconeogenesispathwayinflammatorykinasebregionspace

Features
Gene ID: ENSG00000184163
  
Biological name :C1QTNF12
  
Synonyms : C1q and TNF related 12 / C1QTNF12 / Q5T7M4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.33
Gene start: 1242446
Gene end: 1246722
  
Corresponding Affymetrix probe sets: 243292_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000329137
NCBI entrez gene - 388581     See in Manteia.
OMIM - 616593
RefSeq - XM_011541437
RefSeq - NM_001014980
RefSeq - XM_011541435
RefSeq - XM_011541436
RefSeq Peptide - NP_001014980
swissprot - Q5T7M4
Ensembl - ENSG00000184163
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 A1A5X5ENSDARG00000070681Danio rerio
 C1QTNF12ENSGALG00000001857Gallus gallus
 Q8R2Z0ENSMUSG00000023571Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ERFE / Q4G0M1 / erythroferroneENSG0000017875233


Protein motifs (from Interpro)
Interpro ID Name
 IPR001073  C1q domain
 IPR008983  Tumour necrosis factor-like domain superfamily


Gene Ontology (GO)
cell communicationregulation of molecular functioncellular response to stimuluscellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processmacromolecule localizationresponse to chemicalestablishment of localizationregulation of biological qualitycellular localizationbiosynthetic processresponse to endogenous stimulusresponse to stressresponse to external stimuluscell communicationregulation of molecular functioncellular response to stimuluscellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processmacromolecule localizationresponse to chemicalestablishment of localizationregulation of biological qualitycellular localizationbiosynthetic processresponse to endogenous stimulusresponse to stressresponse to external stimuluscell communicationregulation of molecular functioncellular response to stimuluscellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processmacromolecule localizationresponse to chemicalestablishment of localizationregulation of biological qualitycellular localizationbiosynthetic processresponse to endogenous stimulusresponse to stressresponse to external stimuluscell communicationregulation of molecular functioncellular response to stimuluscellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processmacromolecule localizationresponse to chemicalestablishment of localizationregulation of biological qualitycellular localizationbiosynthetic processresponse to endogenous stimulusresponse to stressresponse to external stimuluscell communicationregulation of molecular functioncellular response to stimuluscellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processmacromolecule localizationresponse to chemicalestablishment of localizationregulation of biological qualitycellular localizationbiosynthetic processresponse to endogenous stimulusresponse to stressresponse to external stimuluscell communicationregulation of molecular functioncellular response to stimuluscellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processmacromolecule localizationresponse to chemicalestablishment of localizationregulation of biological qualitycellular localizationbiosynthetic processresponse to endogenous stimulusresponse to stressresponse to external stimuluscell communicationregulation of molecular functioncellular response to stimuluscellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processmacromolecule localizationresponse to chemicalestablishment of localizationregulation of biological qualitycellular localizationbiosynthetic processresponse to endogenous stimulusresponse to stressresponse to external stimuluscell communicationregulation of molecular functioncellular response to stimuluscellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processmacromolecule localizationresponse to chemicalestablishment of localizationregulation of biological qualitycellular localizationbiosynthetic processresponse to endogenous stimulusresponse to stressresponse to external stimuluscell communicationregulation of molecular functioncellular response to stimuluscellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processmacromolecule localizationresponse to chemicalestablishment of localizationregulation of biological qualitycellular localizationbiosynthetic processresponse to endogenous stimulusresponse to stressresponse to external stimuluscell communicationregulation of molecular functioncellular response to stimuluscellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processmacromolecule localizationresponse to chemicalestablishment of localizationregulation of biological qualitycellular localizationbiosynthetic processresponse to endogenous stimulusresponse to stressresponse to external stimuluscell comcell communicationregulatiregulation of molecular functioncellularcellular response to stimuluscellularcellular metabolic processprimary primary metabolic processsmall mosmall molecule metabolic processorganic organic substance metabolic processmacromolmacromolecule localizationresponseresponse to chemicalestablisestablishment of localizationregulatiregulation of biological qualitycellularcellular localizationbiosynthbiosynthetic processresponseresponse to endogenous stimulusresponseresponse to stressresponseresponse to external stimulus
protein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingprotein bindingreceptor regulator activityreceptor regulator activity
extracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular region
TypeGO IDTermEv.Code
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010906 regulation of glucose metabolic process IEA
 biological_processGO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus IEA
 biological_processGO:0045721 negative regulation of gluconeogenesis IEA
 biological_processGO:0046324 regulation of glucose import IEA
 biological_processGO:0046326 positive regulation of glucose import IEA
 biological_processGO:0046628 positive regulation of insulin receptor signaling pathway IEA
 biological_processGO:0050728 negative regulation of inflammatory response IEA
 biological_processGO:0051897 positive regulation of protein kinase B signaling IEA
 cellular_componentGO:0005576 extracellular region ISS
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0005179 hormone activity ISS
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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