ENSG00000186188


Homo sapiens

Features
Gene ID: ENSG00000186188
  
Biological name :FFAR4
  
Synonyms : FFAR4 / free fatty acid receptor 4 / Q5NUL3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q23.33
Gene start: 93566665
Gene end: 93604480
  
Corresponding Affymetrix probe sets: 240856_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000360536
Ensembl peptide - ENSP00000360538
Ensembl peptide - ENSP00000474477
NCBI entrez gene - 338557     See in Manteia.
OMIM - 609044
RefSeq - NM_001195755
RefSeq - NM_181745
RefSeq Peptide - NP_001182684
RefSeq Peptide - NP_859529
swissprot - Q5NUL3
swissprot - S4R3L2
Ensembl - ENSG00000186188
  
Related genetic diseases (OMIM): 607514 - {Obesity, susceptibility to}, 607514
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FFAR4ENSGALG00000026733Gallus gallus
 Ffar4ENSMUSG00000054200Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0010827 regulation of glucose transmembrane transport IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0045444 fat cell differentiation IEA
 biological_processGO:0046879 hormone secretion IEA
 biological_processGO:0050710 negative regulation of cytokine secretion IEA
 biological_processGO:0050728 negative regulation of inflammatory response IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030139 endocytic vesicle IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0005504 fatty acid binding IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0008527 taste receptor activity IEA


Pathways (from Reactome)
Pathway description
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
G alpha (q) signalling events
Free fatty acid receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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