Manteia

ENSG00000186818

Homo sapiens

Features

Gene ID:	ENSG00000186818

Biological name :	LILRB4

Synonyms :	leukocyte immunoglobulin like receptor B4 / LILRB4 / Q8NHJ6

Possible biological names infered from orthology :

Species:	Homo sapiens

Chr. number:	19
Strand:	1
Band:	q13.42
Gene start:	54643889
Gene end:	54670359

Corresponding Affymetrix probe sets:	1569504_at (Human Genome U133 Plus 2.0 Array) 210152_at (Human Genome U133 Plus 2.0 Array)

Cross references:	Ensembl peptide - ENSP00000270452 Ensembl peptide - ENSP00000483357 Ensembl peptide - ENSP00000408995 Ensembl peptide - ENSP00000401962 Ensembl peptide - ENSP00000375616 Ensembl peptide - ENSP00000375614 Ensembl peptide - ENSP00000375613 NCBI entrez gene - 11006 See in Manteia. OMIM - 604821 RefSeq - XM_017026217 RefSeq - NM_001278426 RefSeq - NM_001278427 RefSeq - NM_001278428 RefSeq - NM_001278429 RefSeq - XM_017026215 RefSeq - XM_017026216 RefSeq Peptide - NP_001265358 RefSeq Peptide - NP_001265355 RefSeq Peptide - NP_001265356 RefSeq Peptide - NP_001265357 swissprot - A8MUE1 swissprot - A0A0A0MSZ8 swissprot - A0A0A0MS20 swissprot - A0A0A0MQW7 swissprot - Q8NHJ6 swissprot - C9JST2 swissprot - A0A087X0F8 Ensembl - ENSG00000186818

See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name

Species

No match

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
LILRB3 / O75022 / leukocyte immunoglobulin like receptor B3	ENSG00000204577	66
LILRB1 / leukocyte immunoglobulin like receptor B1	ENSG00000104972	62
LILRB2 / Q8N423 / leukocyte immunoglobulin like receptor B2	ENSG00000131042	49
LILRB5 / O75023 / leukocyte immunoglobulin like receptor B5	ENSG00000105609	48
LILRA6 / Q6PI73 / leukocyte immunoglobulin like receptor A6	ENSG00000244482	36
A6NI73 / LILRA5 / leukocyte immunoglobulin like receptor A5	ENSG00000187116	34
LILRA4 / P59901 / leukocyte immunoglobulin like receptor A4	ENSG00000239961	33
LILRA1 / O75019 / leukocyte immunoglobulin like receptor A1	ENSG00000104974	31
LILRA2 / Q8N149 / leukocyte immunoglobulin like receptor A2	ENSG00000239998	31
GP6 / Q9HCN6 / glycoprotein VI platelet	ENSG00000088053	26
NCR1 / O76036 / natural cytotoxicity triggering receptor 1	ENSG00000189430	25
KIR3DL3 / killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3	ENSG00000242019	25
P43630 / KIR3DL2 / killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2	ENSG00000240403	23
P43629 / KIR3DL1 / killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1	ENSG00000167633	22
FCAR / P24071 / Fc fragment of IgA receptor	ENSG00000186431	20
Q9H7L2 / KIR3DX1 / killer cell immunoglobulin like receptor, three Ig domains X1	ENSG00000104970	17
P43628 / KIR2DL3 / killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3	ENSG00000243772	16
P43626 / KIR2DL1 / killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1	ENSG00000125498	15
Q99706 / KIR2DL4 / killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	ENSG00000189013	13
KIR2DS4 / killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4	ENSG00000221957	11

Protein motifs (from Interpro)

Interpro ID	Name
IPR007110	Immunoglobulin-like domain
IPR013151	Immunoglobulin
IPR013783	Immunoglobulin-like fold
IPR036179	Immunoglobulin-like domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0002250	adaptive immune response	IEA
biological_process	GO:0002376	immune system process	IEA
biological_process	GO:0007165	signal transduction	TAS
biological_process	GO:0045591	positive regulation of regulatory T cell differentiation	IDA
biological_process	GO:0045671	negative regulation of osteoclast differentiation	IDA
biological_process	GO:0050860	negative regulation of T cell receptor signaling pathway	IDA
biological_process	GO:1900181	negative regulation of protein localization to nucleus	IDA
biological_process	GO:1902894	negative regulation of pri-miRNA transcription by RNA polymerase II	IDA
cellular_component	GO:0005886	plasma membrane	NAS
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
cellular_component	GO:0070062	extracellular exosome	HDA
molecular_function	GO:0003823	antigen binding	TAS
molecular_function	GO:0005515	protein binding	IPI

Pathways (from Reactome)

Pathway description

Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr