ENSG00000197253


Homo sapiens

Features
Gene ID: ENSG00000197253
  
Biological name :TPSB2
  
Synonyms : P20231 / TPSB2 / tryptase beta 2 (gene/pseudogene)
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: -1
Band: p13.3
Gene start: 1227272
Gene end: 1230184
  
Corresponding Affymetrix probe sets: 205683_x_at (Human Genome U133 Plus 2.0 Array)   207134_x_at (Human Genome U133 Plus 2.0 Array)   210084_x_at (Human Genome U133 Plus 2.0 Array)   215382_x_at (Human Genome U133 Plus 2.0 Array)   216474_x_at (Human Genome U133 Plus 2.0 Array)   217023_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000478695
Ensembl peptide - ENSP00000484461
Ensembl peptide - ENSP00000482743
NCBI entrez gene - 64499     See in Manteia.
OMIM - 191081
RefSeq - NM_024164
RefSeq Peptide - NP_077078
swissprot - A0A140VJT7
swissprot - A0A087X1U0
swissprot - A0A087WUI4
swissprot - P20231
Ensembl - ENSG00000197253
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Tpsab1ENSMUSG00000024173Mus musculus
 Tpsb2ENSMUSG00000033825Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q15661 / TPSAB1 / tryptase alpha/beta 1ENSG0000017223699
TPSD1 / Q9BZJ3 / tryptase delta 1ENSG0000009591772
PRSS50 / Q9UI38 / serine protease 50ENSG0000020654933
PRSS50 / Q9UI38 / serine protease 50ENSG0000028370633
PRSS40A / serine protease 40AENSG0000018329217
PRSS40B / serine protease 40BENSG0000018476115


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0031012 extracellular matrix IDA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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