ENSG00000198785


Homo sapiens

Features
Gene ID: ENSG00000198785
  
Biological name :GRIN3A
  
Synonyms : glutamate ionotropic receptor NMDA type subunit 3A / GRIN3A / Q8TCU5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q31.1
Gene start: 101569353
Gene end: 101738580
  
Corresponding Affymetrix probe sets: 233171_at (Human Genome U133 Plus 2.0 Array)   233220_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000355155
NCBI entrez gene - 116443     See in Manteia.
OMIM - 606650
RefSeq - NM_133445
RefSeq Peptide - NP_597702
swissprot - Q8TCU5
Ensembl - ENSG00000198785
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 grin3aENSDARG00000075802Danio rerio
 GRIN3AENSGALG00000015551Gallus gallus
 Grin3aENSMUSG00000039579Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GRIN3B / O60391 / glutamate ionotropic receptor NMDA type subunit 3BENSG0000011603246
GRIN2B / Q13224 / glutamate ionotropic receptor NMDA type subunit 2BENSG0000027307923
GRIN2C / Q14957 / glutamate ionotropic receptor NMDA type subunit 2CENSG0000016150922
GRIN2A / Q12879 / glutamate ionotropic receptor NMDA type subunit 2AENSG0000018345422
GRIN2D / O15399 / glutamate ionotropic receptor NMDA type subunit 2DENSG0000010546421
GRIN1 / Q05586 / glutamate ionotropic receptor NMDA type subunit 1ENSG0000017688419
GRIK5 / Q16478 / glutamate ionotropic receptor kainate type subunit 5ENSG0000010573716
GRIK1 / P39086 / glutamate ionotropic receptor kainate type subunit 1ENSG0000017118916
GRIA2 / P42262 / glutamate ionotropic receptor AMPA type subunit 2ENSG0000012025115
GRIA3 / P42263 / glutamate ionotropic receptor AMPA type subunit 3ENSG0000012567515
GRIK4 / Q16099 / glutamate ionotropic receptor kainate type subunit 4ENSG0000014940315
GRID2 / O43424 / glutamate ionotropic receptor delta type subunit 2ENSG0000015220815
GRIA4 / P48058 / glutamate ionotropic receptor AMPA type subunit 4ENSG0000015257815
GRIA1 / P42261 / glutamate ionotropic receptor AMPA type subunit 1ENSG0000015551115
GRIK3 / Q13003 / glutamate ionotropic receptor kainate type subunit 3ENSG0000016387315
GRIK2 / Q13002 / glutamate ionotropic receptor kainate type subunit 2ENSG0000016441815
GRID1 / Q9ULK0 / glutamate ionotropic receptor delta type subunit 1ENSG0000018277114


Protein motifs (from Interpro)
Interpro ID Name
 IPR001320  Ionotropic glutamate receptor
 IPR001508  Ionotropic glutamate receptor, metazoa
 IPR019594  Ionotropic glutamate receptor, L-glutamate and glycine-binding domain
 IPR028082  Periplasmic binding protein-like I


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0016358 dendrite development IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0035235 ionotropic glutamate receptor signaling pathway IEA
 biological_processGO:0045471 response to ethanol IDA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:0060134 prepulse inhibition IEA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane NAS
 cellular_componentGO:0017146 NMDA selective glutamate receptor complex IDA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0043005 neuron projection IDA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004970 ionotropic glutamate receptor activity IEA
 molecular_functionGO:0004972 NMDA glutamate receptor activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005234 extracellularly glutamate-gated ion channel activity IEA
 molecular_functionGO:0005262 calcium channel activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016594 glycine binding IDA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0051721 protein phosphatase 2A binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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