ENSG00000214943


Homo sapiens
receptorGPR33membranesignalingpathwayg-proteincoupledactivityrhodopsin-likecomplementsignalplasmaintegralcomponentgprotein-coupledformylpeptidereceptor-relatedgpcrtmmediatedinflammatoryresponsetransductionphospholipasec-activatingregulationcytosoliccalciumion

Features
Gene ID: ENSG00000214943
  
Biological name :GPR33
  
Synonyms : GPR33 / G protein-coupled receptor 33 (gene/pseudogene) / Q49SQ1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q12
Gene start: 31482875
Gene end: 31488142
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000421557
NCBI entrez gene - 2856     See in Manteia.
OMIM - 610118
RefSeq - NM_001197184
RefSeq Peptide - NP_001184113
swissprot - Q49SQ1
Ensembl - ENSG00000214943
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fpr1ENSDARG00000042984Danio rerio
 GPR33ENSGALG00000030888Gallus gallus
 Gpr33ENSMUSG00000035148Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CMKLR1 / Q99788 / chemerin chemokine-like receptor 1ENSG0000017460035
FPR2 / P25090 / formyl peptide receptor 2ENSG0000017104931
C3AR1 / Q16581 / complement C3a receptor 1ENSG0000017186031
FPR3 / P25089 / formyl peptide receptor 3ENSG0000018747430
FPR1 / P21462 / formyl peptide receptor 1ENSG0000017105129
PTGDR2 / Q9Y5Y4 / prostaglandin D2 receptor 2ENSG0000018313428
GPR1 / P46091 / G protein-coupled receptor 1ENSG0000018367128
GPR32 / O75388 / G protein-coupled receptor 32ENSG0000014251126
C5AR1 / P21730 / complement C5a receptor 1ENSG0000019740526
GPR152 / Q8TDT2 / G protein-coupled receptor 152ENSG0000017551424
C5AR2 / Q9P296 / complement component 5a receptor 2ENSG0000013483020


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000826  Formyl peptide receptor-related
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
immune responsecell communicationcellular response to stimulusresponse to stressregulation of biological qualitylocalization of cellmovement of cell or subcellular componentresponse to external stimulusresponse to chemicalimmune responsecell communicationcellular response to stimulusresponse to stressregulation of biological qualitylocalization of cellmovement of cell or subcellular componentresponse to external stimulusresponse to chemicalimmune responsecell communicationcellular response to stimulusresponse to stressregulation of biological qualitylocalization of cellmovement of cell or subcellular componentresponse to external stimulusresponse to chemicalimmune responsecell communicationcellular response to stimulusresponse to stressregulation of biological qualitylocalization of cellmovement of cell or subcellular componentresponse to external stimulusresponse to chemicalimmune responsecell communicationcellular response to stimulusresponse to stressregulation of biological qualitylocalization of cellmovement of cell or subcellular componentresponse to external stimulusresponse to chemicalimmune responsecell communicationcellular response to stimulusresponse to stressregulation of biological qualitylocalization of cellmovement of cell or subcellular componentresponse to external stimulusresponse to chemicalimmune responsecell communicationcellular response to stimulusresponse to stressregulation of biological qualitylocalization of cellmovement of cell or subcellular componentresponse to external stimulusresponse to chemicalimmune responsecell communicationcellular response to stimulusresponse to stressregulation of biological qualitylocalization of cellmovement of cell or subcellular componentresponse to external stimulusresponse to chemicalimmune responsecell communicationcellular response to stimulusresponse to stressregulation of biological qualitylocalization of cellmovement of cell or subcellular componentresponse to external stimulusresponse to chemicalimmune responsecell communicationcellular response to stimulusresponse to stressregulation of biological qualitylocalization of cellmovement of cell or subcellular componentresponse to external stimulusresponse to chemicalimmune responseimmune responsecell communicatcell communicationcellular responcellular response to stimulusresponse to strresponse to stressregulation of bregulation of biological qualitylocalization oflocalization of cellmovement of celmovement of cell or subcellular componentresponse to extresponse to external stimulusresponse to cheresponse to chemical
signaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activity
cellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellcellmembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0002430 complement receptor mediated signaling pathway IBA
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway IBA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IBA
 biological_processGO:0050900 leukocyte migration IBA
 biological_processGO:0060326 cell chemotaxis IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004875 complement receptor activity IBA
 molecular_functionGO:0004930 G-protein coupled receptor activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr