ENSG00000231500


Homo sapiens
ribosomalproteinsRPS18bindingcomplextranslationdecayrrnamembraneribosomesubunitformationmrnaprocessingtranslationalinitiationsrp-dependentcotranslationaltargetingviralcytosolsmallexpressionnonsensemediatednmdexonjunctionejc-like

Features
Gene ID: ENSG00000231500
  
Biological name :RPS18
  
Synonyms : P62269 / ribosomal protein S18 / RPS18
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p21.32
Gene start: 33272010
Gene end: 33276510
  
Corresponding Affymetrix probe sets: 201049_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000393241
Ensembl peptide - ENSP00000434837
NCBI entrez gene - 6222     See in Manteia.
OMIM - 180473
RefSeq - NM_022551
RefSeq Peptide - NP_072045
swissprot - P62269
swissprot - J3JS69
Ensembl - ENSG00000231500
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rps18ENSDARG00000100392Danio rerio
 Rps18ENSMUSG00000008668Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001892  Ribosomal protein S13
 IPR010979  Ribosomal protein S13-like, H2TH
 IPR018269  Ribosomal protein S13, conserved site
 IPR027437  30s ribosomal protein S13, C-terminal


Gene Ontology (GO)
nitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsnitrogen comnitrogen compound metabolic processcatabolic prcatabolic processcellular metcellular metabolic processprimary metaprimary metabolic processorganic subsorganic substance metabolic processcellular comcellular component biogenesisbiosyntheticbiosynthetic processmacromoleculmacromolecule localizationestablishmenestablishment of localizationcellular loccellular localizationinterspeciesinterspecies interaction between organisms
organic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomestructural constituent of ribosomeprotein bindingprotein binding
protein-containing complexcellorganellemembrane-enclosed lumencell junctionmembraneextracellular regionprotein-containing complexcellorganellemembrane-enclosed lumencell junctionmembraneextracellular regionprotein-containing complexcellorganellemembrane-enclosed lumencell junctionmembraneextracellular regionprotein-containing complexcellorganellemembrane-enclosed lumencell junctionmembraneextracellular regionprotein-containing complexcellorganellemembrane-enclosed lumencell junctionmembraneextracellular regionprotein-containing complexcellorganellemembrane-enclosed lumencell junctionmembraneextracellular regionprotein-containing complexcellorganellemembrane-enclosed lumencell junctionmembraneextracellular regionprotein-containing complexcellorganellemembrane-enclosed lumencell junctionmembraneextracellular regionprotein-containing complexcellorganellemembrane-enclosed lumencell junctionmembraneextracellular regionprotein-containing complexcellorganellemembrane-enclosed lumencell junctionmembraneextracellular regionprotein-containing cprotein-containing complexcellcellorganelleorganellemembrane-enclosed lumembrane-enclosed lumencell junctioncell junctionmembranemembraneextracellular regionextracellular region
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS
 biological_processGO:0006364 rRNA processing TAS
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation TAS
 biological_processGO:0006614 SRP-dependent cotranslational protein targeting to membrane TAS
 biological_processGO:0019083 viral transcription TAS
 biological_processGO:0042254 ribosome biogenesis IBA
 cellular_componentGO:0005581 collagen trimer IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0015935 small ribosomal subunit HDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0022627 cytosolic small ribosomal subunit IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003735 structural constituent of ribosome IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019843 rRNA binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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