ENSG00000240857


Homo sapiens

Features
Gene ID: ENSG00000240857
  
Biological name :RDH14
  
Synonyms : Q9HBH5 / RDH14 / retinol dehydrogenase 14
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: p24.2
Gene start: 18554723
Gene end: 18560680
  
Corresponding Affymetrix probe sets: 222203_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000370648
NCBI entrez gene - 57665     See in Manteia.
OMIM - 616796
RefSeq - NM_020905
RefSeq Peptide - NP_065956
swissprot - Q53RX3
swissprot - Q9HBH5
Ensembl - ENSG00000240857
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rdh14aENSDARG00000039299Danio rerio
 rdh14bENSDARG00000002467Danio rerio
 RDH14ENSGALG00000019873Gallus gallus
 Rdh14ENSMUSG00000020621Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RDH13 / Q8NBN7 / retinol dehydrogenase 13ENSG0000016043946
RDH11 / Q8TC12 / retinol dehydrogenase 11 (all-trans/9-cis/11-cis)ENSG0000007204243
RDH12 / Q96NR8 / retinol dehydrogenase 12 (all-trans/9-cis/11-cis)ENSG0000013998842
DHRS13 / Q6UX07 / dehydrogenase/reductase 13ENSG0000016753641
DHRSX / Q8N5I4 / dehydrogenase/reductase X-linkedENSG0000016908438
WWOX / Q9NZC7 / WW domain containing oxidoreductaseENSG0000018615336
A0PJE2 / DHRS12 / dehydrogenase/reductase 12ENSG0000010279626


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001649 osteoblast differentiation HDA
 biological_processGO:0042572 retinol metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005765 lysosomal membrane HDA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane HDA
 molecular_functionGO:0008106 alcohol dehydrogenase (NADP+) activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IBA
 molecular_functionGO:0052650 NADP-retinol dehydrogenase activity TAS


Pathways (from Reactome)
Pathway description
RA biosynthesis pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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