ENSG00000241563


Homo sapiens
receptorCORTg-proteincoupledsignalingactivitysomatostatinpathwayextracellularhormonecortistatinc-terminaladenylatecyclase-inhibitingchemicalsynaptictransmissionregulationregionspacebindingneuropeptidepeptideligand-bindingreceptorsgalphasignallingevents

Features
Gene ID: ENSG00000241563
  
Biological name :CORT
  
Synonyms : CORT / cortistatin / O00230
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p36.22
Gene start: 10449719
Gene end: 10451902
  
Corresponding Affymetrix probe sets: 210182_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000366248
NCBI entrez gene - 1325     See in Manteia.
OMIM - 602784
RefSeq - NM_001302
RefSeq Peptide - NP_001293
swissprot - O00230
Ensembl - ENSG00000241563
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CortENSMUSG00000028971Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004250  Somatostatin
 IPR018142  Somatostatin/Cortistatin, C-terminal


Gene Ontology (GO)
cell communicationcellular response to stimulusregulation of molecular functioncell communicationcellular response to stimulusregulation of molecular functioncell communicationcellular response to stimulusregulation of molecular functioncell communicationcellular response to stimulusregulation of molecular functioncell communicationcellular response to stimulusregulation of molecular functioncell communicationcellular response to stimulusregulation of molecular functioncell communicationcellular response to stimulusregulation of molecular functioncell communicationcellular response to stimulusregulation of molecular functioncell communicationcellular response to stimulusregulation of molecular functioncell communicationcellular response to stimulusregulation of molecular functioncell communicationcell communicationcellular response to stimuluscellular response to stimulusregulation of molecular functionregulation of molecular function
protein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingprotein bindingreceptor regulator activityreceptor regulator activity
extracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular region
TypeGO IDTermEv.Code
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway IDA
 biological_processGO:0007268 chemical synaptic transmission NAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space NAS
 molecular_functionGO:0001664 G-protein coupled receptor binding IPI
 molecular_functionGO:0005179 hormone activity IEA
 molecular_functionGO:0005184 neuropeptide hormone activity IDA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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