ENSG00000249853


Homo sapiens

Features
Gene ID: ENSG00000249853
  
Biological name :HS3ST5
  
Synonyms : heparan sulfate-glucosamine 3-sulfotransferase 5 / HS3ST5 / Q8IZT8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: q22.1
Gene start: 114055586
Gene end: 114343045
  
Corresponding Affymetrix probe sets: 240479_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000427888
Ensembl peptide - ENSP00000440332
NCBI entrez gene - 222537     See in Manteia.
OMIM - 609407
RefSeq - XM_017010474
RefSeq - NM_153612
RefSeq - XM_017010472
RefSeq - XM_017010473
RefSeq - XM_006715379
RefSeq - XM_011535588
RefSeq - XM_017010470
RefSeq - XM_017010471
RefSeq Peptide - NP_705840
swissprot - Q8IZT8
Ensembl - ENSG00000249853
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HS3ST5ENSGALG00000026594Gallus gallus
 Hs3st5ENSMUSG00000044499Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HS3ST1 / O14792 / heparan sulfate-glucosamine 3-sulfotransferase 1ENSG0000000258744
Q9Y662 / HS3ST3B1 / heparan sulfate-glucosamine 3-sulfotransferase 3B1ENSG0000012543040
Q9Y663 / HS3ST3A1 / heparan sulfate-glucosamine 3-sulfotransferase 3A1ENSG0000015397640
HS3ST4 / Q9Y661 / heparan sulfate-glucosamine 3-sulfotransferase 4ENSG0000018260140
HS3ST2 / Q9Y278 / heparan sulfate-glucosamine 3-sulfotransferase 2ENSG0000012225437
HS3ST6 / Q96QI5 / heparan sulfate-glucosamine 3-sulfotransferase 6ENSG0000016204034
NDST2 / P52849 / N-deacetylase and N-sulfotransferase 2ENSG0000016650727
NDST4 / Q9H3R1 / N-deacetylase and N-sulfotransferase 4ENSG0000013865326
NDST1 / P52848 / N-deacetylase and N-sulfotransferase 1ENSG0000007061425
NDST3 / O95803 / N-deacetylase and N-sulfotransferase 3ENSG0000016410025
AC022400.6 / bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 isoform 2 ENSG0000027291621


Protein motifs (from Interpro)
Interpro ID Name
 IPR000863  Sulfotransferase domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR037359  Heparan sulfate sulfotransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006024 glycosaminoglycan biosynthetic process TAS
 biological_processGO:0006477 protein sulfation IDA
 biological_processGO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification IDA
 biological_processGO:0046596 regulation of viral entry into host cell IDA
 biological_processGO:0050819 negative regulation of coagulation IDA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008146 sulfotransferase activity IEA
 molecular_functionGO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity TAS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0050656 3"-phosphoadenosine 5"-phosphosulfate binding NAS


Pathways (from Reactome)
Pathway description
HS-GAG biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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