ENSG00000253148


Homo sapiens

Features
Gene ID: ENSG00000253148
  
Biological name :RGS21
  
Synonyms : Q2M5E4 / regulator of G protein signaling 21 / RGS21
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q31.2
Gene start: 192316992
Gene end: 192367285
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000428343
NCBI entrez gene - 431704     See in Manteia.
OMIM - 612407
RefSeq - NM_001039152
RefSeq Peptide - NP_001034241
swissprot - Q2M5E4
Ensembl - ENSG00000253148
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rgs1ENSDARG00000089077Danio rerio
 RGS21ENSGALG00000023897Gallus gallus
 Rgs21ENSMUSG00000098509Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RGS2 / P41220 / regulator of G protein signaling 2ENSG0000011674153
RGS1 / Q08116 / regulator of G protein signaling 1ENSG0000009010451
RGS5 / O15539 / regulator of G protein signaling 5ENSG0000014324847
RGS18 / Q9NS28 / regulator of G protein signaling 18ENSG0000015068147
RGS4 / P49798 / regulator of G protein signaling 4ENSG0000011715245
RGS8 / P57771 / regulator of G protein signaling 8ENSG0000013582445
RGS3 / P49796 / regulator of G protein signaling 3ENSG0000013883545
RGS16 / O15492 / regulator of G protein signaling 16ENSG0000014333344
RGS17 / Q9UGC6 / regulator of G protein signaling 17ENSG0000009184441
RGS13 / O14921 / regulator of G protein signaling 13ENSG0000012707439
RGS20 / O76081 / regulator of G protein signaling 20ENSG0000014750939
RGS19 / P49795 / regulator of G protein signaling 19ENSG0000017170038


Protein motifs (from Interpro)
Interpro ID Name
 IPR016137  RGS domain
 IPR024066  RGS, subdomain 1/3
 IPR036305  RGS domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009968 negative regulation of signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IBA
 molecular_functionGO:0005096 GTPase activator activity IBA


Pathways (from Reactome)
Pathway description
G alpha (q) signalling events
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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