ENSG00000265681


Homo sapiens
lRPL17ribosomalproteindecaytranslationsubuniteukaryoticmrnarrnaprocessingtranslationalsrp-dependentcotranslationaltargetingmembraneviralcytosolribosomelargebindingexpressionsnonsensemediatednmdexonjunctioncomplexejcarchaeal

Features
Gene ID: ENSG00000265681
  
Biological name :RPL17
  
Synonyms : P18621 / ribosomal protein L17 / RPL17
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: -1
Band: q21.1
Gene start: 49488453
Gene end: 49492523
  
Corresponding Affymetrix probe sets: 200038_s_at (Human Genome U133 Plus 2.0 Array)   212270_x_at (Human Genome U133 Plus 2.0 Array)   212537_x_at (Human Genome U133 Plus 2.0 Array)   214291_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000480215
Ensembl peptide - ENSP00000464586
Ensembl peptide - ENSP00000480555
Ensembl peptide - ENSP00000482577
Ensembl peptide - ENSP00000481587
Ensembl peptide - ENSP00000481145
Ensembl peptide - ENSP00000461910
Ensembl peptide - ENSP00000462023
Ensembl peptide - ENSP00000462203
Ensembl peptide - ENSP00000462385
Ensembl peptide - ENSP00000462508
Ensembl peptide - ENSP00000462944
Ensembl peptide - ENSP00000463490
Ensembl peptide - ENSP00000463842
Ensembl peptide - ENSP00000463885
NCBI entrez gene - 6139     See in Manteia.
OMIM - 603661
RefSeq - NM_000985
RefSeq - NM_001035006
RefSeq - NM_001199340
RefSeq - NM_001199341
RefSeq - NM_001199342
RefSeq - NM_001199343
RefSeq - NM_001199344
RefSeq - NM_001199345
RefSeq Peptide - NP_001030178
RefSeq Peptide - NP_001186270
RefSeq Peptide - NP_001186271
RefSeq Peptide - NP_001186272
RefSeq Peptide - NP_001186273
RefSeq Peptide - NP_001186274
RefSeq Peptide - NP_001186269
RefSeq Peptide - NP_000976
swissprot - J3KRX5
swissprot - J3KSJ0
swissprot - J3QQT2
swissprot - J3QLC8
swissprot - J3QS96
swissprot - A0A024R261
swissprot - P18621
swissprot - A0A087WY81
swissprot - A0A087WXM6
swissprot - A0A087WWH0
swissprot - J3KRB3
Ensembl - ENSG00000265681
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rpl17ENSDARG00000057556Danio rerio
 ENSGALG00000040263Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RPL17-C18orf32 / RPL17-C18orf32 readthroughENSG0000021547293


Protein motifs (from Interpro)
Interpro ID Name
 IPR001063  Ribosomal protein L22/L17
 IPR005721  Ribosomal protein L22/L17, eukaryotic/archaeal
 IPR018260  Ribosomal protein L22/L17, conserved site
 IPR036394  Ribosomal protein L22/L17 superfamily


Gene Ontology (GO)
nitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsnitrogen comnitrogen compound metabolic processcatabolic prcatabolic processcellular metcellular metabolic processprimary metaprimary metabolic processorganic subsorganic substance metabolic processcellular comcellular component biogenesisbiosyntheticbiosynthetic processmacromoleculmacromolecule localizationestablishmenestablishment of localizationcellular loccellular localizationinterspeciesinterspecies interaction between organisms
organic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomestructural constituent of ribosomeprotein bindingprotein binding
cellorganelleprotein-containing complexcellorganelleprotein-containing complexcellorganelleprotein-containing complexcellorganelleprotein-containing complexcellorganelleprotein-containing complexcellorganelleprotein-containing complexcellorganelleprotein-containing complexcellorganelleprotein-containing complexcellorganelleprotein-containing complexcellorganelleprotein-containing complexcellcellorganelleorganelleprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS
 biological_processGO:0006364 rRNA processing TAS
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation TAS
 biological_processGO:0006614 SRP-dependent cotranslational protein targeting to membrane TAS
 biological_processGO:0019083 viral transcription TAS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0015934 large ribosomal subunit IEA
 cellular_componentGO:0022625 cytosolic large ribosomal subunit HDA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003735 structural constituent of ribosome IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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