ENSGALG00000000241


Gallus gallus
cholesterolSTARD4domainregulationtransportbindingstartstart-likesuperfamilyesterificationinvolvedstorageintracellularimportbileacidbiosyntheticprocessmitochondrioncytoplasmicvesiclelipidtransporteractivitypregnenolonebiosynthesis

Features
Gene ID: ENSGALG00000000241
  
Biological name :STARD4
  
Synonyms : STARD4 / stAR-related lipid transfer protein 4
  
Possible biological names infered from orthology : Q96DR4 / StAR related lipid transfer domain containing 4 / StAR-related lipid transfer (START) domain containing 4
  
Species: Gallus gallus
  
Chr. number: Z
Strand: 1
Band:
Gene start: 46509914
Gene end: 46518374
  
Corresponding Affymetrix probe sets: Gga.15316.1.S1_s_at (Chicken Array)   GgaAffx.12320.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000000319
NCBI entrez gene - 769322     See in Manteia.
RefSeq - NM_001079742
RefSeq - XM_015280436
RefSeq Peptide - NP_001073210
swissprot - F1NKR7
Ensembl - ENSGALG00000000241
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stard4ENSDARG00000102477Danio rerio
 Q96DR4ENSG00000164211Homo sapiens
 Stard4ENSMUSG00000024378Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
STARD5 / StAR related lipid transfer domain containing 5 / Q9EPQ7* / Q9NSY2* / StAR-related lipid transfer (START) domain containing 5*ENSGALG0000002119336


Protein motifs (from Interpro)
Interpro ID Name
 IPR002913  START domain
 IPR023393  START-like domain superfamily


Gene Ontology (GO)
cellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationregulation of biological qualitycellular localizationbiosynthetic processsmall molecule metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationregulation of biological qualitycellular localizationbiosynthetic processsmall molecule metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationregulation of biological qualitycellular localizationbiosynthetic processsmall molecule metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationregulation of biological qualitycellular localizationbiosynthetic processsmall molecule metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationregulation of biological qualitycellular localizationbiosynthetic processsmall molecule metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationregulation of biological qualitycellular localizationbiosynthetic processsmall molecule metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationregulation of biological qualitycellular localizationbiosynthetic processsmall molecule metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationregulation of biological qualitycellular localizationbiosynthetic processsmall molecule metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationregulation of biological qualitycellular localizationbiosynthetic processsmall molecule metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationregulation of biological qualitycellular localizationbiosynthetic processsmall molecule metabolic processcellular metabocellular metabolic processprimary metabolprimary metabolic processorganic substanorganic substance metabolic processmacromolecule lmacromolecule localizationestablishment oestablishment of localizationregulation of bregulation of biological qualitycellular localicellular localizationbiosynthetic prbiosynthetic processsmall molecule small molecule metabolic process
lipid bindingorganic cyclic compound bindingsmall molecule bindinglipid transporter activitylipid bindingorganic cyclic compound bindingsmall molecule bindinglipid transporter activitylipid bindingorganic cyclic compound bindingsmall molecule bindinglipid transporter activitylipid bindingorganic cyclic compound bindingsmall molecule bindinglipid transporter activitylipid bindingorganic cyclic compound bindingsmall molecule bindinglipid transporter activitylipid bindingorganic cyclic compound bindingsmall molecule bindinglipid transporter activitylipid bindingorganic cyclic compound bindingsmall molecule bindinglipid transporter activitylipid bindingorganic cyclic compound bindingsmall molecule bindinglipid transporter activitylipid bindingorganic cyclic compound bindingsmall molecule bindinglipid transporter activitylipid bindingorganic cyclic compound bindingsmall molecule bindinglipid transporter activitylipid bindinglipid bindingorganic cyclic compound bindingorganic cyclic compound bindingsmall molecule bindingsmall molecule bindinglipid transporter activitylipid transporter activity
cellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellcellorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0010873 positive regulation of cholesterol esterification IEA
 biological_processGO:0010879 cholesterol transport involved in cholesterol storage IEA
 biological_processGO:0032367 intracellular cholesterol transport IEA
 biological_processGO:0070508 cholesterol import IEA
 biological_processGO:0070859 positive regulation of bile acid biosynthetic process IEA
 cellular_componentGO:0005739 mitochondrion IBA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0015485 cholesterol binding IEA
 molecular_functionGO:0017127 cholesterol transporter activity IEA


Pathways (from Reactome)
Pathway description
Pregnenolone biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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