ENSGALG00000001021


Gallus gallus

Features
Gene ID: ENSGALG00000001021
  
Biological name :MYOCD
  
Synonyms : myocardin / MYOCD
  
Possible biological names infered from orthology : Q8IZQ8 / Q8VIM5
  
Species: Gallus gallus
  
Chr. number: 18
Strand: -1
Band:
Gene start: 832279
Gene end: 865063
  
Corresponding Affymetrix probe sets: Gga.19659.1.S1_at (Chicken Array)   GgaAffx.658.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000001505
NCBI entrez gene - 427790     See in Manteia.
RefSeq - XM_015295175
RefSeq - NM_001080715
RefSeq - XM_015295172
RefSeq - XM_015295173
RefSeq - XM_015295167
RefSeq - XM_015295168
RefSeq - XM_015295169
RefSeq - XM_015295170
RefSeq - XM_015295171
RefSeq Peptide - NP_001074184
swissprot - E1BQY3
Ensembl - ENSGALG00000001021
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkeyp-69b9.3ENSDARG00000088881Danio rerio
 MYOCDENSG00000141052Homo sapiens
 MyocdENSMUSG00000020542Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MKL2 / MKL1/myocardin like 2 / Q9ULH7*ENSGALG0000000302638
MKL1 / megakaryoblastic leukemia (translocation) 1 / Q8K4J6* / Q969V6* / MKL/myocardin-like protein 1 *ENSGALG0000001202438


Protein motifs (from Interpro)
Interpro ID Name
 IPR003034  SAP domain
 IPR004018  RPEL repeat
 IPR028721  Myocardin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001560 regulation of cell growth by extracellular stimulus IEA
 biological_processGO:0001570 vasculogenesis IEA
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0003231 cardiac ventricle development IEA
 biological_processGO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0010667 negative regulation of cardiac muscle cell apoptotic process IEA
 biological_processGO:0010832 negative regulation of myotube differentiation IEA
 biological_processGO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0035065 regulation of histone acetylation IEA
 biological_processGO:0035886 vascular smooth muscle cell differentiation IEA
 biological_processGO:0042692 muscle cell differentiation IEA
 biological_processGO:0043388 positive regulation of DNA binding IEA
 biological_processGO:0043954 cellular component maintenance IEA
 biological_processGO:0045661 regulation of myoblast differentiation IEA
 biological_processGO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0045987 positive regulation of smooth muscle contraction IEA
 biological_processGO:0048286 lung alveolus development IEA
 biological_processGO:0048565 digestive tract development IEA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0051145 smooth muscle cell differentiation IEA
 biological_processGO:0051152 positive regulation of smooth muscle cell differentiation IEA
 biological_processGO:0055007 cardiac muscle cell differentiation IEA
 biological_processGO:0055012 ventricular cardiac muscle cell differentiation IEA
 biological_processGO:0060065 uterus development IEA
 biological_processGO:0060157 urinary bladder development IEA
 biological_processGO:0097070 ductus arteriosus closure IEA
 biological_processGO:1900222 negative regulation of amyloid-beta clearance IEA
 biological_processGO:1900239 regulation of phenotypic switching IEA
 biological_processGO:1901228 positive regulation of transcription from RNA polymerase II promoter involved in heart development IEA
 biological_processGO:1904706 negative regulation of vascular smooth muscle cell proliferation IEA
 biological_processGO:1904753 negative regulation of vascular associated smooth muscle cell migration IEA
 biological_processGO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway IEA
 biological_processGO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation IEA
 biological_processGO:2000727 positive regulation of cardiac muscle cell differentiation IEA
 biological_processGO:2001015 negative regulation of skeletal muscle cell differentiation IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000987 proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001046 core promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001076 transcription factor activity, RNA polymerase II transcription factor binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0035035 histone acetyltransferase binding IEA
 molecular_functionGO:0042826 histone deacetylase binding IEA
 molecular_functionGO:0070412 R-SMAD binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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