ENSGALG00000001606


Gallus gallus

Features
Gene ID: ENSGALG00000001606
  
Biological name :INPP5B
  
Synonyms : inositol polyphosphate-5-phosphatase B / INPP5B
  
Possible biological names infered from orthology : P32019 / Q8K337 / Type II inositol 1,4,5-trisphosphate 5-phosphatase
  
Species: Gallus gallus
  
Chr. number: 23
Strand: 1
Band:
Gene start: 3536305
Gene end: 3552479
  
Corresponding Affymetrix probe sets: Gga.12952.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000057648
Ensembl peptide - ENSGALP00000002441
NCBI entrez gene - 419609     See in Manteia.
RefSeq - XM_417756
RefSeq - XM_015297778
RefSeq - XM_015297779
RefSeq - XM_015297776
RefSeq - XM_015297777
swissprot - F1NLK6
swissprot - A0A1D5PXF3
Ensembl - ENSGALG00000001606
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 inpp5bENSDARG00000103683Danio rerio
 INPP5BENSG00000204084Homo sapiens
 Inpp5bENSMUSG00000028894Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
OCRL / OCRL, inositol polyphosphate-5-phosphatase / Q01968* / Q6NVF0* / Inositol polyphosphate 5-phosphatase OCRL-1 *ENSGALG0000000392047
SYNJ1 / synaptojanin 1 / O43426*ENSGALG0000003431723
SYNJ2 / synaptojanin 2 / O15056* / Q9D2G5*ENSGALG0000001372722
INPPL1 / inositol polyphosphate phosphatase like 1 / O15357* / Q6P549* / Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 *ENSGALG0000000433618
INPP5D / inositol polyphosphate-5-phosphatase D / Q92835* / Q9ES52* / Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 *ENSGALG0000003549816
INPP5K / inositol polyphosphate 5-phosphatase K / Q8C5L6* / Q9BT40*ENSGALG0000000273915
INPP5J / inositol polyphosphate-5-phosphatase J / P59644* / Q15735* / Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A *ENSGALG0000002326615
INPP5E / inositol polyphosphate-5-phosphatase E / Q9JII1* / Q9NRR6* / 72 kDa inositol polyphosphate 5-phosphatase *ENSGALG0000000196413


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR000300  Inositol polyphosphate-related phosphatase
 IPR005135  Endonuclease/exonuclease/phosphatase
 IPR008936  Rho GTPase activation protein
 IPR031896  INPP5B, PH domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0030317 flagellated sperm motility IEA
 biological_processGO:0046856 phosphatidylinositol dephosphorylation IEA
 biological_processGO:0070613 regulation of protein processing IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity IEA
 molecular_functionGO:0052745 inositol phosphate phosphatase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of IP2, IP, and Ins in the cytosol
Synthesis of IP3 and IP4 in the cytosol
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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