ENSGALG00000002057


Gallus gallus
rnaPOLR2Dpolymeraseiitranscriptionmrnainitiationcomplexpromoterbindingdna-formationelongationtc-nersplicingrpbrpccoreprocessnucleusprocessingregulationdna-directedsingle-strandedactivitypolrepairgenespathwayhrdc

Features
Gene ID: ENSGALG00000002057
  
Biological name :POLR2D
  
Synonyms : POLR2D / RNA polymerase II subunit D
  
Possible biological names infered from orthology : DNA-directed RNA polymerase II subunit RPB4 / O15514 / Q9D7M8
  
Species: Gallus gallus
  
Chr. number: 9
Strand: -1
Band:
Gene start: 1448566
Gene end: 1452013
  
Corresponding Affymetrix probe sets: Gga.4766.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000003195
NCBI entrez gene - 424754     See in Manteia.
RefSeq - NM_001277409
RefSeq Peptide - NP_001264338
swissprot - F1P2S1
Ensembl - ENSGALG00000002057
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 polr2dENSDARG00000076509Danio rerio
 O15514ENSG00000144231Homo sapiens
 Polr2dENSMUSG00000024258Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002121  HRDC domain
 IPR005574  RNA polymerase subunit RPB4/RPC9
 IPR006590  RNA polymerase Rpb4/RPC9, core
 IPR010997  HRDC-like superfamily


Gene Ontology (GO)
nitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processresponse to stressmacromolecule localizationestablishment of localizationcellular localizationcellular response to stimulusresponse to abiotic stimulusprotein-containing complex localizationcellular component organizationcellular component biogenesisnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processresponse to stressmacromolecule localizationestablishment of localizationcellular localizationcellular response to stimulusresponse to abiotic stimulusprotein-containing complex localizationcellular component organizationcellular component biogenesisnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processresponse to stressmacromolecule localizationestablishment of localizationcellular localizationcellular response to stimulusresponse to abiotic stimulusprotein-containing complex localizationcellular component organizationcellular component biogenesisnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processresponse to stressmacromolecule localizationestablishment of localizationcellular localizationcellular response to stimulusresponse to abiotic stimulusprotein-containing complex localizationcellular component organizationcellular component biogenesisnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processresponse to stressmacromolecule localizationestablishment of localizationcellular localizationcellular response to stimulusresponse to abiotic stimulusprotein-containing complex localizationcellular component organizationcellular component biogenesisnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processresponse to stressmacromolecule localizationestablishment of localizationcellular localizationcellular response to stimulusresponse to abiotic stimulusprotein-containing complex localizationcellular component organizationcellular component biogenesisnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processresponse to stressmacromolecule localizationestablishment of localizationcellular localizationcellular response to stimulusresponse to abiotic stimulusprotein-containing complex localizationcellular component organizationcellular component biogenesisnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processresponse to stressmacromolecule localizationestablishment of localizationcellular localizationcellular response to stimulusresponse to abiotic stimulusprotein-containing complex localizationcellular component organizationcellular component biogenesisnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processresponse to stressmacromolecule localizationestablishment of localizationcellular localizationcellular response to stimulusresponse to abiotic stimulusprotein-containing complex localizationcellular component organizationcellular component biogenesisnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processresponse to stressmacromolecule localizationestablishment of localizationcellular localizationcellular response to stimulusresponse to abiotic stimulusprotein-containing complex localizationcellular component organizationcellular component biogenesisnitrogen nitrogen compound metabolic processcataboliccatabolic processcellular cellular metabolic processprimary mprimary metabolic processorganic sorganic substance metabolic processbiosynthebiosynthetic processresponse response to stressmacromolemacromolecule localizationestablishestablishment of localizationcellular cellular localizationcellular cellular response to stimulusresponse response to abiotic stimulusprotein-cprotein-containing complex localizationcellular cellular component organizationcellular cellular component biogenesis
organic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activitycatalytic activity, acting on RNAprotein bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activitycatalytic activity, acting on RNAprotein bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activitycatalytic activity, acting on RNAprotein bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activitycatalytic activity, acting on RNAprotein bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activitycatalytic activity, acting on RNAprotein bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activitycatalytic activity, acting on RNAprotein bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activitycatalytic activity, acting on RNAprotein bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activitycatalytic activity, acting on RNAprotein bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activitycatalytic activity, acting on RNAprotein bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activitycatalytic activity, acting on RNAprotein bindingorganic cyclic compoundorganic cyclic compound bindingheterocyclic compound bheterocyclic compound bindingsmall molecule bindingsmall molecule bindingtransferase activitytransferase activitycatalytic activity, actcatalytic activity, acting on RNAprotein bindingprotein binding
cellprotein-containing complexorganellemembrane-enclosed lumencellprotein-containing complexorganellemembrane-enclosed lumencellprotein-containing complexorganellemembrane-enclosed lumencellprotein-containing complexorganellemembrane-enclosed lumencellprotein-containing complexorganellemembrane-enclosed lumencellprotein-containing complexorganellemembrane-enclosed lumencellprotein-containing complexorganellemembrane-enclosed lumencellprotein-containing complexorganellemembrane-enclosed lumencellprotein-containing complexorganellemembrane-enclosed lumencellprotein-containing complexorganellemembrane-enclosed lumencellcellprotein-containing complexprotein-containing complexorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumen
TypeGO IDTermEv.Code
 biological_processGO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IBA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter IBA
 biological_processGO:0031990 mRNA export from nucleus in response to heat stress IBA
 biological_processGO:0034402 recruitment of 3"-end processing factors to RNA polymerase II holoenzyme complex IBA
 biological_processGO:0044237 cellular metabolic process IEA
 biological_processGO:0045948 positive regulation of translational initiation IBA
 cellular_componentGO:0000932 P-body IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005665 DNA-directed RNA polymerase II, core complex IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003697 single-stranded DNA binding IBA
 molecular_functionGO:0003727 single-stranded RNA binding IBA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003899 DNA-directed 5"-3" RNA polymerase activity IBA
 molecular_functionGO:0031369 translation initiation factor binding IBA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Transcriptional regulation by small RNAs
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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