ENSGALG00000002578


Gallus gallus
gamma-secretasenotchprocessingactivityintegralsubunitaph-signalingpathwayreceptorproteinregulationcatalyticendoplasmicreticulumplasmacomplexendopeptidase

Features
Gene ID: ENSGALG00000002578
  
Biological name :
  
Synonyms :
  
Possible biological names infered from orthology :
  
Species: Gallus gallus
  
Chr. number: Z
Strand: 1
Band:
Gene start: 9221595
Gene end: 9225213
  
Corresponding Affymetrix probe sets: Gga.2367.1.S1_at (Chicken Array)   Gga.2367.2.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000004055
NCBI entrez gene - 769986     See in Manteia.
RefSeq - XM_001233301
swissprot - E1C2N9
Ensembl - ENSGALG00000002578
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:114200ENSDARG00000100633Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
APH1A / aph-1 homolog A, gamma-secretase subunit / Q8BVF7* / Q96BI3* / Gamma-secretase subunit APH-1A *ENSGALG0000004516359


Protein motifs (from Interpro)
Interpro ID Name
 IPR009294  Gamma-secretase subunit Aph-1


Gene Ontology (GO)
cell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functioncell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functioncell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functioncell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functioncell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functioncell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functioncell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functioncell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functioncell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functioncell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functioncell communicationcell communicationcellular response tocellular response to stimulusnitrogen compound menitrogen compound metabolic processcellular metabolic pcellular metabolic processprimary metabolic prprimary metabolic processorganic substance meorganic substance metabolic processregulation of molecuregulation of molecular function
catalytic activity, acting on a proteinhydrolase activitycatalytic activity, acting on a proteinhydrolase activitycatalytic activity, acting on a proteinhydrolase activitycatalytic activity, acting on a proteinhydrolase activitycatalytic activity, acting on a proteinhydrolase activitycatalytic activity, acting on a proteinhydrolase activitycatalytic activity, acting on a proteinhydrolase activitycatalytic activity, acting on a proteinhydrolase activitycatalytic activity, acting on a proteinhydrolase activitycatalytic activity, acting on a proteinhydrolase activitycatalytic activity, acting on a proteincatalytic activity, acting on a proteinhydrolase activityhydrolase activity
cellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellcellorganelleorganellemembranemembraneprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0007219 Notch signaling pathway IBA
 biological_processGO:0007220 Notch receptor processing IBA
 biological_processGO:0016485 protein processing IBA
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 cellular_componentGO:0005783 endoplasmic reticulum IBA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070765 gamma-secretase complex IBA
 molecular_functionGO:0004175 endopeptidase activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   


© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr