ENSGALG00000002634


Gallus gallus
regulationHDAC3histonetranscriptiondeacetylasebindingactivityproteindna-templateddeacetylationrnapolymeraseiichromatinfactornucleusspindlehfamilydomainphosphorylationorganizationstabilitytorsignalingobsoleteimportjnkcascadeassemblycellular

Features
Gene ID: ENSGALG00000002634
  
Biological name :HDAC3
  
Synonyms : HDAC3 / histone deacetylase 3
  
Possible biological names infered from orthology : O15379
  
Species: Gallus gallus
  
Chr. number: 13
Strand: -1
Band:
Gene start: 1905650
Gene end: 1919540
  
Corresponding Affymetrix probe sets: Gga.2110.1.S1_at (Chicken Array)   Gga.2110.1.S2_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000004141
NCBI entrez gene - 395506     See in Manteia.
RefSeq - NM_204747
RefSeq Peptide - NP_990078
swissprot - F1NH59
Ensembl - ENSGALG00000002634
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hdac3ENSDARG00000037514Danio rerio
 HDAC3ENSG00000171720Homo sapiens
 Hdac3ENSMUSG00000024454Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HDAC2 / histone deacetylase 2 / Q92769*ENSGALG0000001499158
HDAC1 / P56517 / Histone deacetylase 1 / O09106* / Q13547* / Gm10093*ENSGALG0000000329754
HDAC8 / histone deacetylase 8 / Q8VH37* / Q9BY41*ENSGALG0000000482535
HDAC11 / histone deacetylase 11 / Q91WA3* / Q96DB2*ENSGALG0000000509218


Protein motifs (from Interpro)
Interpro ID Name
 IPR000286  Histone deacetylase family
 IPR003084  Histone deacetylase
 IPR023801  Histone deacetylase domain


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationregulation of biological qualitycell communicationcellular response to stimulusresponse to stresscellular component biogenesiscell cyclemicrotubule-based processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationregulation of biological qualitycell communicationcellular response to stimulusresponse to stresscellular component biogenesiscell cyclemicrotubule-based processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationregulation of biological qualitycell communicationcellular response to stimulusresponse to stresscellular component biogenesiscell cyclemicrotubule-based processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationregulation of biological qualitycell communicationcellular response to stimulusresponse to stresscellular component biogenesiscell cyclemicrotubule-based processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationregulation of biological qualitycell communicationcellular response to stimulusresponse to stresscellular component biogenesiscell cyclemicrotubule-based processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationregulation of biological qualitycell communicationcellular response to stimulusresponse to stresscellular component biogenesiscell cyclemicrotubule-based processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationregulation of biological qualitycell communicationcellular response to stimulusresponse to stresscellular component biogenesiscell cyclemicrotubule-based processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationregulation of biological qualitycell communicationcellular response to stimulusresponse to stresscellular component biogenesiscell cyclemicrotubule-based processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationregulation of biological qualitycell communicationcellular response to stimulusresponse to stresscellular component biogenesiscell cyclemicrotubule-based processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component organizationregulation of biological qualitycell communicationcellular response to stimulusresponse to stresscellular component biogenesiscell cyclemicrotubule-based processnitrogen cnitrogen compound metabolic processbiosynthetbiosynthetic processcellular mcellular metabolic processprimary meprimary metabolic processorganic suorganic substance metabolic processcellular ccellular component organizationregulationregulation of biological qualitycell commucell communicationcellular rcellular response to stimulusresponse tresponse to stresscellular ccellular component biogenesiscell cyclecell cyclemicrotubulmicrotubule-based process
chromatin bindingtranscription coregulator activitycatalytic activity, acting on a proteinhydrolase activityprotein bindingion bindingchromatin bindingtranscription coregulator activitycatalytic activity, acting on a proteinhydrolase activityprotein bindingion bindingchromatin bindingtranscription coregulator activitycatalytic activity, acting on a proteinhydrolase activityprotein bindingion bindingchromatin bindingtranscription coregulator activitycatalytic activity, acting on a proteinhydrolase activityprotein bindingion bindingchromatin bindingtranscription coregulator activitycatalytic activity, acting on a proteinhydrolase activityprotein bindingion bindingchromatin bindingtranscription coregulator activitycatalytic activity, acting on a proteinhydrolase activityprotein bindingion bindingchromatin bindingtranscription coregulator activitycatalytic activity, acting on a proteinhydrolase activityprotein bindingion bindingchromatin bindingtranscription coregulator activitycatalytic activity, acting on a proteinhydrolase activityprotein bindingion bindingchromatin bindingtranscription coregulator activitycatalytic activity, acting on a proteinhydrolase activityprotein bindingion bindingchromatin bindingtranscription coregulator activitycatalytic activity, acting on a proteinhydrolase activityprotein bindingion bindingchromatin bindingchromatin bindingtranscription coregulattranscription coregulator activitycatalytic activity, actcatalytic activity, acting on a proteinhydrolase activityhydrolase activityprotein bindingprotein bindingion bindingion binding
cellorganellemembrane-enclosed lumensupramolecular complexmembraneprotein-containing complexcellorganellemembrane-enclosed lumensupramolecular complexmembraneprotein-containing complexcellorganellemembrane-enclosed lumensupramolecular complexmembraneprotein-containing complexcellorganellemembrane-enclosed lumensupramolecular complexmembraneprotein-containing complexcellorganellemembrane-enclosed lumensupramolecular complexmembraneprotein-containing complexcellorganellemembrane-enclosed lumensupramolecular complexmembraneprotein-containing complexcellorganellemembrane-enclosed lumensupramolecular complexmembraneprotein-containing complexcellorganellemembrane-enclosed lumensupramolecular complexmembraneprotein-containing complexcellorganellemembrane-enclosed lumensupramolecular complexmembraneprotein-containing complexcellorganellemembrane-enclosed lumensupramolecular complexmembraneprotein-containing complexcellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumensupramolecular complexsupramolecular complexmembranemembraneprotein-containing compprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001934 positive regulation of protein phosphorylation IEA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006476 protein deacetylation IEA
 biological_processGO:0016575 histone deacetylation IEA
 biological_processGO:0031647 regulation of protein stability IEA
 biological_processGO:0032008 positive regulation of TOR signaling IEA
 biological_processGO:0042993 obsolete positive regulation of transcription factor import into nucleus IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046329 negative regulation of JNK cascade IEA
 biological_processGO:0051225 spindle assembly IEA
 biological_processGO:0070932 histone H3 deacetylation IEA
 biological_processGO:0071498 cellular response to fluid shear stress IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005876 spindle microtubule IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0017053 transcriptional repressor complex IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0004407 histone deacetylase activity IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0030332 cyclin binding IEA
 molecular_functionGO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific) IEA
 molecular_functionGO:0033558 protein deacetylase activity IEA
 molecular_functionGO:0042826 histone deacetylase binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051059 NF-kappaB binding IEA


Pathways (from Reactome)
Pathway description
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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