ENSGALG00000002831


Gallus gallus

Features
Gene ID: ENSGALG00000002831
  
Biological name :SH3PXD2B
  
Synonyms : SH3 and PX domains 2B / SH3PXD2B
  
Possible biological names infered from orthology : A1X283 / A2AAY5 / SH3 and PX domain-containing protein 2B
  
Species: Gallus gallus
  
Chr. number: 13
Strand: 1
Band:
Gene start: 8853753
Gene end: 8918179
  
Corresponding Affymetrix probe sets: Gga.10070.1.S1_at (Chicken Array)   Gga.8707.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000004460
Ensembl peptide - ENSGALP00000057138
Ensembl peptide - ENSGALP00000053036
Ensembl peptide - ENSGALP00000052210
Ensembl peptide - ENSGALP00000044049
NCBI entrez gene - 427625     See in Manteia.
RefSeq - XM_425197
swissprot - E1C4J9
swissprot - A0A1D5PW09
swissprot - A0A1D5PJP0
swissprot - A0A1D5PHD2
swissprot - A0A1D5NUN1
Ensembl - ENSGALG00000002831
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sh3pxd2bENSDARG00000103251Danio rerio
 A1X283ENSG00000174705Homo sapiens
 A2AAY5ENSMUSG00000040711Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SH3PXD2A / SH3 and PX domains 2A / O89032* / Q5TCZ1* / SH3 and PX domain-containing protein 2A *ENSGALG0000000829341
NCF1 / neutrophil cytosol factor 1 / P14598* / Q09014* / neutrophil cytosolic factor 1*ENSGALG0000000118913
NOXO1 / NADPH oxidase organizer 1 / Q8NFA2* / Q8VCM2*ENSGALG0000000557211


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR001655  Neutrophil cytosol factor 1
 IPR001683  Phox homologous domain
 IPR030512  SH3 and PX domain-containing protein 2B


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001501 skeletal system development IEA
 biological_processGO:0001654 eye development IEA
 biological_processGO:0002051 osteoblast fate commitment IEA
 biological_processGO:0006801 superoxide metabolic process IBA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0022617 extracellular matrix disassembly IEA
 biological_processGO:0040018 positive regulation of multicellular organism growth IEA
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 biological_processGO:0045600 positive regulation of fat cell differentiation IEA
 biological_processGO:0048705 skeletal system morphogenesis IEA
 biological_processGO:0051496 positive regulation of stress fiber assembly IEA
 biological_processGO:0055114 oxidation-reduction process IBA
 biological_processGO:0060348 bone development IEA
 biological_processGO:0060378 regulation of brood size IEA
 biological_processGO:0060612 adipose tissue development IEA
 biological_processGO:0071800 podosome assembly IEA
 biological_processGO:0072657 protein localization to membrane IEA
 biological_processGO:1904179 positive regulation of adipose tissue development IEA
 biological_processGO:1904888 cranial skeletal system development IEA
 cellular_componentGO:0002102 podosome IBA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0010314 phosphatidylinositol-5-phosphate binding IBA
 molecular_functionGO:0016175 superoxide-generating NADPH oxidase activity IEA
 molecular_functionGO:0016176 superoxide-generating NADPH oxidase activator activity IBA
 molecular_functionGO:0032266 phosphatidylinositol-3-phosphate binding IBA
 molecular_functionGO:0035091 phosphatidylinositol binding IEA
 molecular_functionGO:0042169 SH2 domain binding IEA
 molecular_functionGO:0070273 phosphatidylinositol-4-phosphate binding IBA
 molecular_functionGO:0080025 phosphatidylinositol-3,5-bisphosphate binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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