ENSGALG00000002981


Gallus gallus

Features
Gene ID: ENSGALG00000002981
  
Biological name :ERCC4
  
Synonyms : ERCC4 / Gallus gallus ERCC excision repair 4, endonuclease catalytic subunit (ERCC4), mRNA.
  
Possible biological names infered from orthology : DNA repair endonuclease XPF / ERCC excision repair 4, endonuclease catalytic subunit / Q92889 / Q9QZD4
  
Species: Gallus gallus
  
Chr. number: 14
Strand: 1
Band:
Gene start: 668703
Gene end: 679472
  
Corresponding Affymetrix probe sets: Gga.4162.1.S1_at (Chicken Array)   GgaAffx.12489.1.A1_at (Chicken Array)   GgaAffx.12489.1.S1_s_at (Chicken Array)   GgaAffx.20236.1.S1_at (Chicken Array)   GgaAffx.25706.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000004707
Ensembl peptide - ENSGALP00000063017
Ensembl peptide - ENSGALP00000062450
NCBI entrez gene - 416420     See in Manteia.
RefSeq - NM_001318411
RefSeq - XM_015294279
RefSeq - XM_414734
RefSeq Peptide - NP_001305340
swissprot - A0A1L1RVZ8
swissprot - A0A1L1RUF6
swissprot - F1NAV2
Ensembl - ENSGALG00000002981
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ercc4ENSDARG00000014161Danio rerio
 ERCC4ENSG00000175595Homo sapiens
 Ercc4ENSMUSG00000022545Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006166  ERCC4 domain
 IPR006167  DNA repair protein XPF
 IPR010994  RuvA domain 2-like
 IPR011335  Restriction endonuclease type II-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000712 resolution of meiotic recombination intermediates IBA
 biological_processGO:0000723 telomere maintenance IEA
 biological_processGO:0000724 double-strand break repair via homologous recombination IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006289 nucleotide-excision repair IEA
 biological_processGO:0006295 nucleotide-excision repair, DNA incision, 3"-to lesion IEA
 biological_processGO:0006296 nucleotide-excision repair, DNA incision, 5"-to lesion IEA
 biological_processGO:0006303 double-strand break repair via nonhomologous end joining IEA
 biological_processGO:0009411 response to UV IEA
 biological_processGO:0009650 UV protection IEA
 biological_processGO:0032205 negative regulation of telomere maintenance IEA
 biological_processGO:0033683 nucleotide-excision repair, DNA incision IEA
 biological_processGO:0034644 cellular response to UV IEA
 biological_processGO:0061819 telomeric DNA-containing double minutes formation IEA
 biological_processGO:1901255 nucleotide-excision repair involved in interstrand cross-link repair IBA
 biological_processGO:1904357 negative regulation of telomere maintenance via telomere lengthening IEA
 biological_processGO:1905765 negative regulation of protection from non-homologous end joining at telomere IEA
 biological_processGO:1905768 negative regulation of double-stranded telomeric DNA binding IEA
 cellular_componentGO:0000109 nucleotide-excision repair complex IEA
 cellular_componentGO:0000110 nucleotide-excision repair factor 1 complex IEA
 cellular_componentGO:0000781 chromosome, telomeric region IEA
 cellular_componentGO:0000784 nuclear chromosome, telomeric region IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005669 transcription factor TFIID complex IEA
 cellular_componentGO:0070522 ERCC4-ERCC1 complex IEA
 molecular_functionGO:0000014 single-stranded DNA endodeoxyribonuclease activity IBA
 molecular_functionGO:0001094 TFIID-class transcription factor binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003684 damaged DNA binding IEA
 molecular_functionGO:0003697 single-stranded DNA binding IBA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004520 endodeoxyribonuclease activity IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0047485 protein N-terminus binding IEA
 molecular_functionGO:1990599 3" overhang single-stranded DNA endodeoxyribonuclease activity IEA


Pathways (from Reactome)
Pathway description
Dual Incision in GG-NER
Dual incision in TC-NER


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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