ENSGALG00000003733


Gallus gallus

Features
Gene ID: ENSGALG00000003733
  
Biological name :LIFR
  
Synonyms : leukemia inhibitory factor receptor precursor / LIFR
  
Possible biological names infered from orthology : LIF receptor alpha / Mus musculus leukemia inhibitory factor receptor (Lifr), transcript variant 3, mRNA. / P42702 / P42703
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 12007504
Gene end: 12048425
  
Corresponding Affymetrix probe sets: Gga.62.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000005914
NCBI entrez gene - 395262     See in Manteia.
RefSeq - NM_204575
RefSeq Peptide - NP_989906
swissprot - F1NN90
Ensembl - ENSGALG00000003733
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lifraENSDARG00000098857Danio rerio
 lifrbENSDARG00000039863Danio rerio
 LIFRENSG00000113594Homo sapiens
 LifrENSMUSG00000054263Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
OSMR / oncostatin M receptor / Q99650*ENSGALG0000000374723
IL6ST / interleukin 6 signal transducer / P40189* / Q00560* / Interleukin-6 receptor subunit beta *ENSGALG0000001471615
IL12RB2 / interleukin-12 receptor subunit beta-2 precursor / P97378* / Q99665* / interleukin 12 receptor subunit beta 2*ENSGALG0000001122214
CSF3R / granulocyte colony-stimulating factor receptor / P40223* / Q99062* / colony stimulating factor 3 receptor*ENSGALG0000000211213
IL31RA / interleukin 31 receptor A / Q8K5B1* / Q8NI17* / Interleukin-31 receptor subunit alpha *ENSGALG0000003080012


Protein motifs (from Interpro)
Interpro ID Name
 IPR003529  Long hematopoietin receptor, Gp130 family 2, conserved site
 IPR003531  Short hematopoietin receptor, family 1, conserved site
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway IEA
 biological_processGO:0034097 response to cytokine IEA
 biological_processGO:0038165 oncostatin-M-mediated signaling pathway IEA
 biological_processGO:0048861 leukemia inhibitory factor signaling pathway IEA
 biological_processGO:0070120 ciliary neurotrophic factor-mediated signaling pathway IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex IEA
 molecular_functionGO:0004896 cytokine receptor activity IEA
 molecular_functionGO:0004897 ciliary neurotrophic factor receptor activity IEA
 molecular_functionGO:0004923 leukemia inhibitory factor receptor activity IEA
 molecular_functionGO:0004924 oncostatin-M receptor activity IEA
 molecular_functionGO:0005127 ciliary neurotrophic factor receptor binding IEA
 molecular_functionGO:0019838 growth factor binding IEA


Pathways (from Reactome)
Pathway description
IL-6-type cytokine receptor ligand interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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