Manteia

ENSGALG00000004581

Gallus gallus

Features

Gene ID:	ENSGALG00000004581

Biological name :	NDST1

Synonyms :	N-deacetylase and N-sulfotransferase 1 / NDST1

Possible biological names infered from orthology :	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 Heparan sulfate N-deacetylase 1 Heparan sulfate N-sulfotransferase 1 / P52848 / Q3UHN9

Species:	Gallus gallus

Chr. number:	13
Strand:	-1
Band:
Gene start:	13114617
Gene end:	13132620

Corresponding Affymetrix probe sets:	GgaAffx.2831.1.S1_at (Chicken Array)

Cross references:	Ensembl peptide - ENSGALP00000007278 Ensembl peptide - ENSGALP00000047711 Ensembl peptide - ENSGALP00000046742 NCBI entrez gene - 416274 See in Manteia. RefSeq - XM_004944945 RefSeq - XM_015293923 swissprot - E1BQI7 swissprot - A0A1D5P4U9 swissprot - A0A1D5P247 Ensembl - ENSGALG00000004581

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
ndst1a	ENSDARG00000062397	Danio rerio
ndst1b	ENSDARG00000103606	Danio rerio
NDST1	ENSG00000070614	Homo sapiens
Ndst1	ENSMUSG00000054008	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
NDST2* / P52850* / P52849* / AC022400.6* / N-deacetylase and N-sulfotransferase 2* / N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2* / bifunctional heparan sulfate N-deacetylase/...	ENSGALG00000005107	76
NDST4 / N-deacetylase and N-sulfotransferase 4 / Q9EQW8* / Q9H3R1* / Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 Heparan sulfate N-deacetylase 4 Heparan sulfate N-sulfot...	ENSGALG00000012015	70
NDST3* / O95803* / Q9EQH7* / N-deacetylase and N-sulfotransferase 3* / N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3*	ENSGALG00000012010	30
NDST3* / O95803* / Q9EQH7* / N-deacetylase and N-sulfotransferase 3* / N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3*	ENSGALG00000038525	13
HS3ST2 / heparan sulfate-glucosamine 3-sulfotransferase 2 / Q673U1* / Q9Y278* / Heparan sulfate glucosamine 3-O-sulfotransferase 2 *	ENSGALG00000040675	11
Q9Y663* / Q8BKN6* / Q9QZS6* / Q9Y662* / HS3ST3A1* / HS3ST3B1* / heparan sulfate-glucosamine 3-sulfotransferase 3A1* / heparan sulfate-glucosamine 3-sulfotransferase 3B1* / Heparan sulfate g...	ENSGALG00000001371	10
HS3ST4 / heparan sulfate-glucosamine 3-sulfotransferase 4 / Q9Y661*	ENSGALG00000006290	10
HS3ST5 / heparan sulfate-glucosamine 3-sulfotransferase 5 / Q8BSL4* / Q8IZT8* / heparan sulfate (glucosamine) 3-O-sulfotransferase 5*	ENSGALG00000026594	10
Q9Y663* / Q8BKN6* / Q9QZS6* / Q9Y662* / HS3ST3A1* / HS3ST3B1* / heparan sulfate-glucosamine 3-sulfotransferase 3A1* / heparan sulfate-glucosamine 3-sulfotransferase 3B1* / Heparan sulfate g...	ENSGALG00000031058	10
	ENSGALG00000006989	9
HS3ST1 / heparan sulfate-glucosamine 3-sulfotransferase 1 / O14792* / O35310* / Heparan sulfate glucosamine 3-O-sulfotransferase 1 *	ENSGALG00000014934	9
NDST3* / O95803* / Q9EQH7* / N-deacetylase and N-sulfotransferase 3* / N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3*	ENSGALG00000046333	7
HS3ST6 / heparan sulfate-glucosamine 3-sulfotransferase 6 / Q5GFD5* / Q96QI5* / Heparan sulfate glucosamine 3-O-sulfotransferase 6 *	ENSGALG00000005413	6

Protein motifs (from Interpro)

Interpro ID	Name
IPR000863	Sulfotransferase domain
IPR021930	Heparan sulphate-N-deacetylase
IPR027417	P-loop containing nucleoside triphosphate hydrolase

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0000271	polysaccharide biosynthetic process	IEA
biological_process	GO:0003279	cardiac septum development	IEA
biological_process	GO:0006477	protein sulfation	IEA
biological_process	GO:0007507	heart development	IEA
biological_process	GO:0007585	respiratory gaseous exchange	IEA
biological_process	GO:0008543	fibroblast growth factor receptor signaling pathway	IEA
biological_process	GO:0009887	animal organ morphogenesis	IEA
biological_process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	IEA
biological_process	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	IEA
biological_process	GO:0030203	glycosaminoglycan metabolic process	IEA
biological_process	GO:0030900	forebrain development	IEA
biological_process	GO:0030901	midbrain development	IEA
biological_process	GO:0035904	aorta development	IEA
biological_process	GO:0043410	positive regulation of MAPK cascade	IEA
biological_process	GO:0045880	positive regulation of smoothened signaling pathway	IEA
biological_process	GO:0048702	embryonic neurocranium morphogenesis	IEA
biological_process	GO:0048703	embryonic viscerocranium morphogenesis	IEA
biological_process	GO:0060976	coronary vasculature development	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
molecular_function	GO:0008146	sulfotransferase activity	IEA
molecular_function	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity	IEA
molecular_function	GO:0016787	hydrolase activity	IEA
molecular_function	GO:0019213	deacetylase activity	IEA
molecular_function	GO:0042328	heparan sulfate N-acetylglucosaminyltransferase activity	IEA

Pathways (from Reactome)

Pathway description

HS-GAG biosynthesis

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr