ENSGALG00000005046


Gallus gallus

Features
Gene ID: ENSGALG00000005046
  
Biological name :SHMT1
  
Synonyms : serine hydroxymethyltransferase 1 / SHMT1
  
Possible biological names infered from orthology : P34896 / P50431 / serine hydroxymethyltransferase 1 (soluble)
  
Species: Gallus gallus
  
Chr. number: 14
Strand: -1
Band:
Gene start: 5132126
Gene end: 5136038
  
Corresponding Affymetrix probe sets: Gga.12929.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000008079
Ensembl peptide - ENSGALP00000058417
Ensembl peptide - ENSGALP00000056350
Ensembl peptide - ENSGALP00000050012
Ensembl peptide - ENSGALP00000047253
Ensembl peptide - ENSGALP00000046229
Ensembl peptide - ENSGALP00000043989
NCBI entrez gene - 416520     See in Manteia.
RefSeq - XM_414824
swissprot - A0A1D5PZK3
swissprot - A0A1D5PTV0
swissprot - A0A1D5PB89
swissprot - E1BS67
swissprot - A0A1D5P0Q1
swissprot - A0A1D5NUH2
swissprot - A0A1D5P3J8
Ensembl - ENSGALG00000005046
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 shmt1ENSDARG00000052816Danio rerio
 SHMT1ENSG00000176974Homo sapiens
 Shmt1ENSMUSG00000020534Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001085  Serine hydroxymethyltransferase
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase
 IPR019798  Serine hydroxymethyltransferase, pyridoxal phosphate binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006231 dTMP biosynthetic process IEA
 biological_processGO:0006544 glycine metabolic process IEA
 biological_processGO:0006563 L-serine metabolic process IEA
 biological_processGO:0006565 L-serine catabolic process IEA
 biological_processGO:0006730 one-carbon metabolic process IEA
 biological_processGO:0009113 purine nucleobase biosynthetic process IEA
 biological_processGO:0017148 negative regulation of translation IEA
 biological_processGO:0019264 glycine biosynthetic process from serine IEA
 biological_processGO:0035999 tetrahydrofolate interconversion IEA
 biological_processGO:0046653 tetrahydrofolate metabolic process IEA
 biological_processGO:0046655 folic acid metabolic process IEA
 biological_processGO:0051262 protein tetramerization IEA
 biological_processGO:0051289 protein homotetramerization IEA
 biological_processGO:1904482 cellular response to tetrahydrofolate IEA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0000900 translation repressor activity, mRNA regulatory element binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004372 glycine hydroxymethyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0048027 mRNA 5"-UTR binding IEA
 molecular_functionGO:0070905 serine binding IEA


Pathways (from Reactome)
Pathway description
Metabolism of folate and pterines
Carnitine synthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr