ENSGALG00000005737


Gallus gallus
gtpaseSGSM2activitydomainintracellulartransportregulationrab-gtpase-tbcrunproteinvesiclefusionlateendosomegolgiactivationcytoplasmendomembranemelanosomeactivatorrabbinding

Features
Gene ID: ENSGALG00000005737
  
Biological name :SGSM2
  
Synonyms : SGSM2 / small G protein signaling modulator 2
  
Possible biological names infered from orthology : O43147 / Q80U12
  
Species: Gallus gallus
  
Chr. number: 19
Strand: 1
Band:
Gene start: 9342165
Gene end: 9386034
  
Corresponding Affymetrix probe sets: GgaAffx.3595.1.S1_s_at (Chicken Array)   GgaAffx.3595.5.S1_at (Chicken Array)   GgaAffx.3595.5.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046692
Ensembl peptide - ENSGALP00000009200
NCBI entrez gene - 417673     See in Manteia.
RefSeq - XM_415919
RefSeq - XM_015295858
RefSeq - XM_015295859
RefSeq - XM_004946789
RefSeq - XM_004946790
RefSeq - XM_004946791
RefSeq - XM_004946792
RefSeq - XM_004946793
RefSeq - XM_004946794
RefSeq - XM_004946795
swissprot - F1N8F2
swissprot - A0A1D5P1Z8
Ensembl - ENSGALG00000005737
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sgsm2ENSDARG00000063307Danio rerio
 SGSM2ENSG00000141258Homo sapiens
 Sgsm2ENSMUSG00000038351Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SGSM1 / small G protein signaling modulator 1 / Q2NKQ1* / Q8BPQ7*ENSGALG0000000537961
TBC1D15 / TBC1 domain family member 15 / Q8TC07* / Q9CXF4*ENSGALG0000001019014
TBC1D16 / TBC1 domain family member 16 / Q8TBP0* / Mus musculus TBC1 domain family, member 16 (Tbc1d16), transcript variant 2, mRNA.*ENSGALG0000000705412


Protein motifs (from Interpro)
Interpro ID Name
 IPR000195  Rab-GTPase-TBC domain
 IPR004012  RUN domain


Gene Ontology (GO)
macromolecule localizationestablishment of localizationcellular localizationcellular component organizationregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationcellular component organizationregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationcellular component organizationregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationcellular component organizationregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationcellular component organizationregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationcellular component organizationregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationcellular component organizationregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationcellular component organizationregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationcellular component organizationregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationcellular component organizationregulation of molecular functionmacromolecule localizationmacromolecule localizationestablishment of localizatioestablishment of localizationcellular localizationcellular localizationcellular component organizatcellular component organizationregulation of molecular funcregulation of molecular function
enzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityenzyme regulator activityprotein bindingprotein binding
cellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellcellorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0031338 regulation of vesicle fusion IBA
 biological_processGO:0034499 late endosome to Golgi transport IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0090630 activation of GTPase activity IBA
 cellular_componentGO:0005622 intracellular IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0012505 endomembrane system IBA
 cellular_componentGO:0042470 melanosome IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0017137 Rab GTPase binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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