ENSGALG00000006593


Gallus gallus
claudinregulationmembraneCLDN18developmentjunctionclaudin-pmp-empmpsuperfamilyconservedsiteboneresorptiondigestivetracttnfsf-mediatedsignalingpathwayproteinlocalizationnucleusosteoclastplasmabicellulartightintegralcomponentcell

Features
Gene ID: ENSGALG00000006593
  
Biological name :CLDN18
  
Synonyms : claudin 18 / CLDN18
  
Possible biological names infered from orthology : P56856 / P56857
  
Species: Gallus gallus
  
Chr. number: 9
Strand: -1
Band:
Gene start: 4121939
Gene end: 4128404
  
Corresponding Affymetrix probe sets: GgaAffx.4104.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000010630
NCBI entrez gene - 429135     See in Manteia.
RefSeq - XM_003641730
RefSeq - XM_426691
swissprot - E1BUC3
Ensembl - ENSGALG00000006593
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FQ377628.1ENSDARG00000103087Danio rerio
 CLDN18ENSG00000066405Homo sapiens
 Cldn18ENSMUSG00000032473Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENSGALG0000003896419
Q9D7U6* / Q8N7P3* / A6NM45* / CLDN22* / CLDN24* / claudin 24* / claudin 22*ENSGALG0000001066218
CLDN10 / claudin-10 isoform 2 precursor / P78369* / Q9Z0S6* / claudin 10*ENSGALG0000001911418
CLDN20 / claudin 20 / P56880*ENSGALG0000002763416
CLDN25 / claudin 25 / C9JDP6*ENSGALG0000000692615


Protein motifs (from Interpro)
Interpro ID Name
 IPR003928  Claudin-18
 IPR004031  PMP-22/EMP/MP20/Claudin superfamily
 IPR006187  Claudin
 IPR017974  Claudin, conserved site


Gene Ontology (GO)
regulation of biological qualitytissue remodelinganatomical structure developmentcell communicationresponse to chemicalcellular response to stimulusmacromolecule localizationcellular localizationcellular developmental processregulation of biological qualitytissue remodelinganatomical structure developmentcell communicationresponse to chemicalcellular response to stimulusmacromolecule localizationcellular localizationcellular developmental processregulation of biological qualitytissue remodelinganatomical structure developmentcell communicationresponse to chemicalcellular response to stimulusmacromolecule localizationcellular localizationcellular developmental processregulation of biological qualitytissue remodelinganatomical structure developmentcell communicationresponse to chemicalcellular response to stimulusmacromolecule localizationcellular localizationcellular developmental processregulation of biological qualitytissue remodelinganatomical structure developmentcell communicationresponse to chemicalcellular response to stimulusmacromolecule localizationcellular localizationcellular developmental processregulation of biological qualitytissue remodelinganatomical structure developmentcell communicationresponse to chemicalcellular response to stimulusmacromolecule localizationcellular localizationcellular developmental processregulation of biological qualitytissue remodelinganatomical structure developmentcell communicationresponse to chemicalcellular response to stimulusmacromolecule localizationcellular localizationcellular developmental processregulation of biological qualitytissue remodelinganatomical structure developmentcell communicationresponse to chemicalcellular response to stimulusmacromolecule localizationcellular localizationcellular developmental processregulation of biological qualitytissue remodelinganatomical structure developmentcell communicationresponse to chemicalcellular response to stimulusmacromolecule localizationcellular localizationcellular developmental processregulation of biological qualitytissue remodelinganatomical structure developmentcell communicationresponse to chemicalcellular response to stimulusmacromolecule localizationcellular localizationcellular developmental processregulation of bregulation of biological qualitytissue remodelitissue remodelinganatomical struanatomical structure developmentcell communicatcell communicationresponse to cheresponse to chemicalcellular responcellular response to stimulusmacromolecule lmacromolecule localizationcellular localicellular localizationcellular develocellular developmental process
cellmembranecell junctioncellmembranecell junctioncellmembranecell junctioncellmembranecell junctioncellmembranecell junctioncellmembranecell junctioncellmembranecell junctioncellmembranecell junctioncellmembranecell junctioncellmembranecell junctioncellcellmembranemembranecell junctioncell junction
TypeGO IDTermEv.Code
 biological_processGO:0045779 negative regulation of bone resorption IEA
 biological_processGO:0048565 digestive tract development IEA
 biological_processGO:0071847 TNFSF11-mediated signaling pathway IEA
 biological_processGO:1900181 negative regulation of protein localization to nucleus IEA
 biological_processGO:2001205 negative regulation of osteoclast development IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0005198 structural molecule activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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