Manteia

ENSGALG00000007121

Gallus gallus

Features

Gene ID:	ENSGALG00000007121

Biological name :	TNFSF8

Synonyms :	TNFSF8 / tumor necrosis factor ligand superfamily member 8

Possible biological names infered from orthology :	P32971 / P32972 / TNF superfamily member 8

Species:	Gallus gallus

Chr. number:	17
Strand:	-1
Band:
Gene start:	3107319
Gene end:	3120947

Corresponding Affymetrix probe sets:	Gga.5181.1.S1_at (Chicken Array)

Cross references:	Ensembl peptide - ENSGALP00000011522 NCBI entrez gene - 378930 See in Manteia. RefSeq - NM_204409 RefSeq Peptide - NP_989740 swissprot - F1N8E9 Ensembl - ENSGALG00000007121

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name

Similarity(%)

No match

Protein motifs (from Interpro)

Interpro ID	Name
IPR006052	Tumour necrosis factor domain
IPR008983	Tumour necrosis factor-like domain superfamily
IPR021184	Tumour necrosis factor, conserved site
IPR021185	Tumour necrosis factor family protein, CD30 ligand type

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006955	immune response	IEA
biological_process	GO:0010469	regulation of signaling receptor activity	IEA
biological_process	GO:0043374	CD8-positive, alpha-beta T cell differentiation	IEA
biological_process	GO:0045944	positive regulation of transcription by RNA polymerase II	IEA
biological_process	GO:0050830	defense response to Gram-positive bacterium	IEA
cellular_component	GO:0005615	extracellular space	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
molecular_function	GO:0005125	cytokine activity	IEA
molecular_function	GO:0005164	tumor necrosis factor receptor binding	IEA

Pathways (from Reactome)

Pathway description

TNFs bind their physiological receptors

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSGALG00000039741	TNFRSF8 / P28908* / Q60846* / TNF receptor superfamily member 8* / Tumor necrosis factor receptor superfamily member 8 *	/ complex / reaction

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr