ENSGALG00000007483


Gallus gallus
repeatsubtypeLRIG1immunoglobulin-likedomainmembranecysteine-richflankingregionc-terminaltypicali-setfoldsuperfamilysensoryperceptionsoundhaircycleprocessotolithmorphogenesisinnervationintegralcomponentsignalingegfrregulationmet

Features
Gene ID: ENSGALG00000007483
  
Biological name :LRIG1
  
Synonyms : leucine rich repeats and immunoglobulin like domains 1 / LRIG1
  
Possible biological names infered from orthology : Leucine-rich repeats and immunoglobulin-like domains protein 1 / P70193 / Q96JA1
  
Species: Gallus gallus
  
Chr. number: 12
Strand: -1
Band:
Gene start: 14473942
Gene end: 14552260
  
Corresponding Affymetrix probe sets: GgaAffx.22257.1.S1_at (Chicken Array)   GgaAffx.22257.2.S1_s_at (Chicken Array)   GgaAffx.22257.3.S1_s_at (Chicken Array)   GgaAffx.4660.1.S1_s_at (Chicken Array)   GgaAffx.4704.1.S1_at (Chicken Array)   GgaAffx.4706.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000035449
NCBI entrez gene - 427592     See in Manteia.
RefSeq - XM_015293263
RefSeq - XM_425165
swissprot - E1C726
Ensembl - ENSGALG00000007483
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lrig1ENSDARG00000075625Danio rerio
 LRIG1ENSG00000144749Homo sapiens
 Lrig1ENSMUSG00000030029Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LRIG3 / leucine rich repeats and immunoglobulin like domains 3 / Q6P1C6* / Q6UXM1* / Leucine-rich repeats and immunoglobulin-like domains protein 3 *ENSGALG0000000975544
LRIG2 / leucine rich repeats and immunoglobulin like domains 2 / O94898* / Q52KR2*ENSGALG0000000173342
ADGRA1 / adhesion G protein-coupled receptor A1 / Q86SQ6* / Q8C4G9*ENSGALG0000000704515
ADGRA3 / adhesion G protein-coupled receptor A3 / Q7TT36* / Q8IWK6*ENSGALG0000003347014
ADGRA2 / adhesion G protein-coupled receptor A2 / Q91ZV8* / Q96PE1*ENSGALG0000000311813
LGI1 / leucine-rich glioma-inactivated protein 1 precursor / O95970* / Q9JIA1* / leucine rich glioma inactivated 1* / Leucine-rich glioma-inactivated protein 1 *ENSGALG000000317209
LGI2 / leucine-rich repeat LGI family member 2 precursor / Q8K4Z0* / Q8N0V4* / leucine rich repeat LGI family member 2*ENSGALG000000432839


Protein motifs (from Interpro)
Interpro ID Name
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
system processmolting cycleanatomical structure developmentsystem processmolting cycleanatomical structure developmentsystem processmolting cycleanatomical structure developmentsystem processmolting cycleanatomical structure developmentsystem processmolting cycleanatomical structure developmentsystem processmolting cycleanatomical structure developmentsystem processmolting cycleanatomical structure developmentsystem processmolting cycleanatomical structure developmentsystem processmolting cycleanatomical structure developmentsystem processmolting cycleanatomical structure developmentsystem processsystem processmolting cyclemolting cycleanatomical structure developmentanatomical structure development
membranemembranemembranemembranemembranemembranemembranemembranemembranemembranemembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0007605 sensory perception of sound IEA
 biological_processGO:0022405 hair cycle process IEA
 biological_processGO:0032474 otolith morphogenesis IEA
 biological_processGO:0060384 innervation IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
Signaling by EGFR
Negative regulation of MET activity


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000036883 MET / hepatocyte growth factor receptor precursor / P08581* / MET proto-oncogene, receptor tyrosine kinase*  / complex / reaction
 ENSGALG00000005894 USP8 / ubiquitin specific peptidase 8 / P40818* / Q80U87*  / reaction






 

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