ENSGALG00000008230


Gallus gallus

Features
Gene ID: ENSGALG00000008230
  
Biological name :PCGF6
  
Synonyms : PCGF6 / polycomb group ring finger 6
  
Possible biological names infered from orthology : Polycomb group RING finger protein 6 / Q99NA9 / Q9BYE7
  
Species: Gallus gallus
  
Chr. number: 6
Strand: -1
Band:
Gene start: 23575063
Gene end: 23596056
  
Corresponding Affymetrix probe sets: Gga.16959.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000013380
NCBI entrez gene - 770712     See in Manteia.
RefSeq - XM_001234042
RefSeq - XM_004942256
swissprot - F1NDM6
Ensembl - ENSGALG00000008230
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pcgf6ENSDARG00000069681Danio rerio
 PCGF6ENSG00000156374Homo sapiens
 Pcgf6ENSMUSG00000025050Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PCGF5 / polycomb group ring finger 5 / Q3UK78* / Q86SE9* / Polycomb group RING finger protein 5 *ENSGALG0000000650223
BMI1 / Q5SDR3 / Polycomb complex protein BMI-1 / P25916* / P35226* / COMMD3-BMI1* / COMMD3-BMI1 readthrough* / BMI1 proto-oncogene, polycomb ring finger*ENSGALG0000004126723
PCGF3 / polycomb group ring finger 3 / Q3KNV8* / Q8BTQ0* / Polycomb group RING finger protein 3 *ENSGALG0000001533322
PCGF2 / P23798* / P35227* / polycomb group ring finger 2* / Polycomb group RING finger protein 2 *ENSGALG0000001881522
PCGF2* / P23798* / P35227* / polycomb group ring finger 2* / Polycomb group RING finger protein 2 *ENSGALG0000004050122


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0036353 histone H2A-K119 monoubiquitination IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0031519 PcG protein complex IEA
 cellular_componentGO:0035102 PRC1 complex IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA


Pathways (from Reactome)
Pathway description
Transcriptional Regulation by E2F6


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000011976 L3MBTL2 / L3MBTL2, polycomb repressive complex 1 subunit / P59178* / Q969R5* / Lethal(3)malignant brain tumor-like protein 2 *  / complex
 ENSGALG00000016454 E2F6 / E2F transcription factor 6 / O54917* / O75461* / Transcription factor E2F6 *  / complex / reaction
 ENSGALG00000011038 CBX3 / Q13185* / chromobox 3* / chromobox protein homolog 3 *  / complex / reaction
 ENSGALG00000016823 TFDP1* / TFDP3* / Q5H9I0* / Q08639* / Q14186* / transcription factor Dp-1* / transcription factor Dp family member 3*  / complex / reaction
 ENSGALG00000009540 YAF2 / YY1 associated factor 2 / Q8IY57* / Q99LW6*  / complex
 ENSGALG00000037219 RNF2 / ring finger protein 2 / Q99496* / Q9CQJ4* / E3 ubiquitin-protein ligase RING2 *  / complex






 

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