ENSGALG00000008532


Gallus gallus
transcriptionrnaiiNELFBelongationpolymeraseregulationcomplexcofactorbrcapromoterdna-templatednucleusnucleoplasmnelfformationpolpre-transcriptioneventstpregulatesdnarepairgenes

Features
Gene ID: ENSGALG00000008532
  
Biological name :NELFB
  
Synonyms : negative elongation factor complex member B / NELFB
  
Possible biological names infered from orthology : negative elongation factor B isoform 1 / Q8WX92
  
Species: Gallus gallus
  
Chr. number: 17
Strand: 1
Band:
Gene start: 2393650
Gene end: 2404789
  
Corresponding Affymetrix probe sets: GgaAffx.5382.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000013889
Ensembl peptide - ENSGALP00000054539
Ensembl peptide - ENSGALP00000054472
NCBI entrez gene - 417254     See in Manteia.
RefSeq - NM_001006202
RefSeq Peptide - NP_001006202
swissprot - A0A1D5PNU5
swissprot - A0A1D5PNM9
swissprot - Q5ZLK9
Ensembl - ENSGALG00000008532
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nelfbENSDARG00000035505Danio rerio
 NELFBENSG00000188986Homo sapiens
 NelfbENSMUSG00000013465Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR010405  Cofactor of BRCA1


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processnitrogen compound metabolic nitrogen compound metabolic processbiosynthetic processbiosynthetic processcellular metabolic processcellular metabolic processprimary metabolic processprimary metabolic processorganic substance metabolic organic substance metabolic process
cellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumenprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter IBA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0032021 NELF complex IBA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA Polymerase II Transcription Elongation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000944 SUPT4H1 / SPT4 homolog, DSIF elongation factor subunit / P63272* / Supt4a* / P63271* / suppressor of Ty 4A*  / complex
 ENSGALG00000002087 NCBP1 / Q5ZJZ6 / Nuclear cap-binding protein subunit 1 / Q09161* / Q3UYV9*  / complex
 ENSGALG00000006843 NCBP2 / A6PVI3* / NCBP2L* / P52298* / Q9CQ49* / nuclear cap binding protein subunit 2* / nuclear cap binding protein subunit 2 like*  / complex
 ENSGALG00000039160 Q5ZI08 / SUPT5H / Transcription elongation factor SPT5 / Supt5* / O55201* / O00267* / SPT5 homolog, DSIF elongation factor subunit*  / complex
 ENSGALG00000031461 CTDP1 / CTD phosphatase subunit 1 / Q7TSG2* / Q9Y5B0* / RNA polymerase II subunit A C-terminal domain phosphatase *  / complex






 

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