ENSGALG00000009545


Gallus gallus
transmembraneSLC25A12mitochondrialtransportef-handdomaincarriermembranel-glutamatecalciumionl-aspartatetransporteractivityproteinpairsubstratesolutecalcium-bindingsitesuperfamilyaspartatemalate-aspartateshuttleresponsemitochondrioninnerintegralcomponentmyelinsheath

Features
Gene ID: ENSGALG00000009545
  
Biological name :SLC25A12
  
Synonyms : SLC25A12 / solute carrier family 25 member 12
  
Possible biological names infered from orthology : O75746 / Q8BH59 / solute carrier family 25 (mitochondrial carrier, Aralar), member 12
  
Species: Gallus gallus
  
Chr. number: 7
Strand: 1
Band:
Gene start: 17998010
Gene end: 18044455
  
Corresponding Affymetrix probe sets: Gga.15866.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000054659
Ensembl peptide - ENSGALP00000055881
Ensembl peptide - ENSGALP00000015519
Ensembl peptide - ENSGALP00000045671
NCBI entrez gene - 431387     See in Manteia.
RefSeq - XM_428938
RefSeq - XM_015289769
RefSeq - XM_015289770
RefSeq - XM_015289771
RefSeq - XM_015289764
RefSeq - XM_015289765
RefSeq - XM_015289766
RefSeq - XM_015289767
RefSeq - XM_015289768
swissprot - A0A1D5PSJ5
swissprot - F1P3D8
swissprot - A0A1D5PP62
Ensembl - ENSGALG00000009545
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 O75746ENSG00000115840Homo sapiens
 Q8BH59ENSMUSG00000027010Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SLC25A13 / solute carrier family 25 member 13 / Q9QXX4* / Q9UJS0* / solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13*ENSGALG0000000972876
SLC25A22 / solute carrier family 25 member 22 / Q9D6M3* / Q9H936* / solute carrier family 25 (mitochondrial carrier, glutamate), member 22*ENSGALG0000003933520


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR002067  Mitochondrial carrier protein
 IPR011992  EF-hand domain pair
 IPR018108  Mitochondrial substrate/solute carrier
 IPR018247  EF-Hand 1, calcium-binding site
 IPR023395  Mitochondrial carrier domain superfamily


Gene Ontology (GO)
establishment of localizationresponse to chemicalcellular metabolic processoxidation-reduction processestablishment of localizationresponse to chemicalcellular metabolic processoxidation-reduction processestablishment of localizationresponse to chemicalcellular metabolic processoxidation-reduction processestablishment of localizationresponse to chemicalcellular metabolic processoxidation-reduction processestablishment of localizationresponse to chemicalcellular metabolic processoxidation-reduction processestablishment of localizationresponse to chemicalcellular metabolic processoxidation-reduction processestablishment of localizationresponse to chemicalcellular metabolic processoxidation-reduction processestablishment of localizationresponse to chemicalcellular metabolic processoxidation-reduction processestablishment of localizationresponse to chemicalcellular metabolic processoxidation-reduction processestablishment of localizationresponse to chemicalcellular metabolic processoxidation-reduction processestablishment of localizationestablishment of localizationresponse to chemicalresponse to chemicalcellular metabolic processcellular metabolic processoxidation-reduction processoxidation-reduction process
neurotransmitter transporter activitytransmembrane transporter activityion bindingneurotransmitter transporter activitytransmembrane transporter activityion bindingneurotransmitter transporter activitytransmembrane transporter activityion bindingneurotransmitter transporter activitytransmembrane transporter activityion bindingneurotransmitter transporter activitytransmembrane transporter activityion bindingneurotransmitter transporter activitytransmembrane transporter activityion bindingneurotransmitter transporter activitytransmembrane transporter activityion bindingneurotransmitter transporter activitytransmembrane transporter activityion bindingneurotransmitter transporter activitytransmembrane transporter activityion bindingneurotransmitter transporter activitytransmembrane transporter activityion bindingneurotransmitter transporter activityneurotransmitter transporter activitytransmembrane transporter activitytransmembrane transporter activityion bindingion binding
cellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellcellorganelleorganellemembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0015810 aspartate transmembrane transport IEA
 biological_processGO:0015813 L-glutamate transmembrane transport IEA
 biological_processGO:0043490 malate-aspartate shuttle IEA
 biological_processGO:0051592 response to calcium ion IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0070778 L-aspartate transmembrane transport IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043209 myelin sheath IEA
 molecular_functionGO:0005313 L-glutamate transmembrane transporter activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0015183 L-aspartate transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
Gluconeogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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